Persistence and load of high‐risk HPV are predictors for development of high‐grade cervical lesions: a longitudinal French cohort study

V Dalstein, D Riethmuller, JL Prétet… - … journal of cancer, 2003 - Wiley Online Library
Oncogenic HPV types are the major cause of worldwide cervical cancer, but only a small
proportion of infected women will develop high‐grade cervical intraepithelial neoplasia or …

[HTML][HTML] Persistence of HPV infection and risk of high-grade cervical intraepithelial neoplasia in a cohort of Colombian women

N Muñoz, G Hernandez-Suarez, F Mendez… - British journal of …, 2009 - nature.com
Little is known about the dynamics of human papillomavirus (HPV) infection and subsequent
development of high-grade cervical intraepithelial neoplasia (CIN2/3), particularly in …

Long‐term risk of cervical intraepithelial neoplasia grade 3 or worse according to high‐risk human papillomavirus genotype and semi‐quantitative viral load among …

LT Thomsen, K Frederiksen, C Munk… - … journal of cancer, 2015 - Wiley Online Library
In this prospective cohort study, we estimated the long‐term risk of cervical intraepithelial
neoplasia grade 3 or cancer (CIN3+) by high‐risk human papillomavirus (hrHPV) genotype …

Viral load as a predictor of the risk of cervical intraepithelial neoplasia

NF Schlecht, A Trevisan… - … journal of cancer, 2003 - Wiley Online Library
HPV infections are believed to be a necessary cause of cervical cancer. Viral burden, as a
surrogate indicator for persistence, may help predict risk of subsequent SIL. We used results …

Determinants of human papillomavirus load among women with histological cervical intraepithelial neoplasia 3: dominant impact of surrounding low-grade lesions

ME Sherman, SS Wang, CM Wheeler, L Rich… - … Biomarkers & Prevention, 2003 - AACR
Measurement of human papillomavirus (HPV) DNA load has been suggested as a means
for improving the positive predictive value of HPV testing for detecting cervical intraepithelial …

Determination of viral load thresholds in cervical scrapings to rule out CIN 3 in HPV 16, 18, 31 and 33‐positive women with normal cytology

PJF Snijders, CJA Hogewoning… - … journal of cancer, 2006 - Wiley Online Library
An increased high‐risk human papillomavirus (hrHPV) viral load in cervical scrapings has
been proposed as a determinant for high‐grade cervical intraepithelial neoplasia (CIN) and …

Risk factors for cervical human papillomavirus infection and high-grade intraepithelial lesion in women aged 20 to 31 years in Germany

C Remschmidt, AM Kaufmann, I Hagemann… - International Journal of …, 2013 - ijgc.bmj.com
Background Persistent infection with high-risk human papillomaviruses (HPVs) can lead to
cervical intraepithelial lesion and cervical cancer. Sexual behavior and smoking have been …

Long‐term HPV type‐specific risks of high‐grade cervical intraepithelial lesions: a 14‐year follow‐up of a randomized primary HPV screening trial

V Smelov, KM Elfström, ALV Johansson… - … journal of cancer, 2015 - Wiley Online Library
Quantitative knowledge of the long‐term human papillomavirus (HPV) type‐specific risks for
high‐grade cervical intraepithelial neoplasias Grades 2 and 3 (CIN2 and CIN3) is useful for …

Cross‐sectional analysis of oncogenic HPV viral load and cervical intraepithelial neoplasia

R Flores, M Papenfuss, WT Klimecki… - … journal of cancer, 2006 - Wiley Online Library
In human papillomavirus (HPV)‐associated carcinogenesis, HPV infection characteristics
such as viral load may play an important role in lesion development. The purpose of this …

[HTML][HTML] Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: a meta-analysis

GM Clifford, JS Smith, T Aguado… - British journal of cancer, 2003 - nature.com
Particular types of human papillomavirus (HPV) infection may preferentially progress from
high-grade squamous intraepithelial lesions (HSIL) to squamous cell carcinoma of the cervix …