Sequential alterations in diffusion metrics as correlates of disease severity in amyotrophic lateral sclerosis
Background and objective The neuropathology of amyotrophic lateral sclerosis (ALS)
follows a regional distribution pattern in the brain with four stages. Using diffusion tensor …
follows a regional distribution pattern in the brain with four stages. Using diffusion tensor …
Longitudinal diffusion tensor imaging-based assessment of tract alterations: an application to amyotrophic lateral sclerosis
D Baldaranov, A Khomenko, I Kobor… - Frontiers in human …, 2017 - frontiersin.org
Objective: The potential of magnetic resonance imaging (MRI) as a technical biomarker for
cerebral microstructural alterations in neurodegenerative diseases is under investigation. In …
cerebral microstructural alterations in neurodegenerative diseases is under investigation. In …
Disease aggressiveness signatures of amyotrophic lateral sclerosis in white matter tracts revealed by the D50 disease progression model
R Steinbach, N Gaur, A Roediger… - Human brain …, 2021 - Wiley Online Library
Numerous neuroimaging studies in amyotrophic lateral sclerosis (ALS) have reported links
between structural changes and clinical data; however phenotypic and disease course …
between structural changes and clinical data; however phenotypic and disease course …
Usefulness of diffusion tensor imaging findings as biomarkers for amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. However, no reliable
biomarkers have been identified to represent the clinical status. This study aimed to …
biomarkers have been identified to represent the clinical status. This study aimed to …
A large-scale multicentre cerebral diffusion tensor imaging study in amyotrophic lateral sclerosis
Objective Damage to the cerebral tissue structural connectivity associated with amyotrophic
lateral sclerosis (ALS), which extends beyond the motor pathways, can be visualised by …
lateral sclerosis (ALS), which extends beyond the motor pathways, can be visualised by …
Tract integrity in amyotrophic lateral sclerosis: 6–month evaluation using MR diffusion tensor imaging
Background This study was performed to assess changes in diffusion tensor imaging (DTI)
over time in patients with amyotrophic lateral sclerosis (ALS). Methods We performed DTI in …
over time in patients with amyotrophic lateral sclerosis (ALS). Methods We performed DTI in …
Fractional anisotropy in the supplementary motor area correlates with disease duration and severity of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is progressive and fatal neurodegenerative disorder with
upper and lower motor neuron signs. There are no biomarkers to track disease progression …
upper and lower motor neuron signs. There are no biomarkers to track disease progression …
Beyond fractional anisotropy in amyotrophic lateral sclerosis: the value of mean, axial, and radial diffusivity and its correlation with electrophysiological conductivity …
AF Geraldo, J Pereira, P Nunes, S Reimão, R Sousa… - Neuroradiology, 2018 - Springer
Purpose This paper aims to analyze the contribution of mean diffusivity (MD), axial diffusivity
(AD), and radial diffusivity (RD) in the detection of microstructural abnormalities in …
(AD), and radial diffusivity (RD) in the detection of microstructural abnormalities in …
Quantitative diffusion tensor imaging in amyotrophic lateral sclerosis
CA Sage, RR Peeters, A Görner, W Robberecht… - Neuroimage, 2007 - Elsevier
OBJECTIVE: Aim of present study was to evaluate changes in diffusion tensor imaging (DTI)
parameters in the whole brain of 28 patients with amyotrophic lateral sclerosis (ALS) …
parameters in the whole brain of 28 patients with amyotrophic lateral sclerosis (ALS) …
Linear associations between clinically assessed upper motor neuron disease and diffusion tensor imaging metrics in amyotrophic lateral sclerosis
JH Woo, S Wang, ER Melhem, JC Gee, A Cucchiara… - PloS one, 2014 - journals.plos.org
Objective To assess the relationship between clinically assessed Upper Motor Neuron
(UMN) disease in Amyotrophic Lateral Sclerosis (ALS) and local diffusion alterations …
(UMN) disease in Amyotrophic Lateral Sclerosis (ALS) and local diffusion alterations …