This study was conducted to determine the effect of an empiric antimicrobial guide on
clinical and economic outcomes related to severe sepsis. As all critical care nurses know …

PURPOSE: The mortality of severe sepsis exceeds 40%. Recently, the treatment of severe
sepsis has focused on management guidelines which incorporate multiple therapeutic …

The Surviving Sepsis Campaign guidelines were published in an effort to increase
awareness and improve outcomes in the management of severe sepsis and septic shock. 1 …

Objectives: Compelling evidence has shown that aggressive resuscitation bundles,
adequate source control, appropriate antibiotic therapy, and organ support are cornerstone …

Objective: To assess appropriate antimicrobial therapy as an outcome determinant in severe
sepsis and septic shock using the number needed to treat. Design: Single-center cohort …

Sepsis mortality may be improved by early recognition and appropriate treatment based on
evidence-based guidelines. An intervention was developed that focused on earlier …

Purpose. Current practices for managing severe sepsis in US hospitals were studied.
Methods. A questionnaire was distributed to nurse managers who were members of the …

Objective A dedicated program with guideline to enhance sepsis care was launched in July
2014 in Emergency Department (ED) of two regional hospitals. The study aimed to evaluate …

Objective A sepsis protocol including institution-specific antibiotic recommendations based
on local susceptibility patterns was implemented at our institution. The purpose of this …

Objectives: To determine if time to initial antimicrobial is associated with progression of
severe sepsis to septic shock. Design: Retrospective cohort. Setting: Six hundred fifty-six …