The endothelium is a thin layer of squamous cells that acts as a semipermeable barrier
regulating vascular permeability to let molecules pass through it thereby maintaining tissue …

Endothelial cells line the inner surface of all blood vessels and constitute a selective barrier
between blood and tissue. Permeation of solutes across the endothelial cell monolayer …

The molecular mechanisms by which endothelial permeability occurs are often studied more
readily in vitro, underscoring the importance of the use of systems that mimic human …

The most frequently used parameters to describe the barrier properties of endothelial cells
(ECs) in vitro are (i) the macromolecular permeability, indicating the flux of a …

Vascular leakage is an important feature in several diseases, such as septic shock, viral
hemorrhagic fever, cancer metastasis and ischemia-reperfusion injuries. Thus establishing …

An essential component of any in vitro model for endothelial permeability is a confluent cell
monolayer. The model reported here utilizes primary human umbilical vein endothelial cells …

Endothelial cells lining the vessels of the vasculature and the cell–cell junctions, which join
them, provide the primary barrier to the passage of fluids, immune cells, and …

Whereas physiological vascular permeability (VP) mediates selective transport of plasma,
electrolytes, proteins, and cells across an intact endothelial barrier, pathological VP results …

Vascular permeability is a pathologic process in many disease states ranging from
metastatic progression of malignancies to ischemia–reperfusion injury. In order to more …

An essential requirement for adequate organ performance is the formation of permeability
barriers that separate and maintain compartments of distinctive structure. The endothelial …