Background Few studies of how exposure of children to anesthesia may affect
neurodevelopment employ comprehensive neuropsychological assessments. This study …

Background Exposure of young animals to general anesthesia causes neurodegeneration
and lasting behavioral abnormalities; whether these findings translate to children remains …

There is increasing evidence that exposure of developing brains in animals, including
nonhuman primates, to commonly-utilized anesthetic agents may cause adverse effects on …

Background We hypothesised that exposure to multiple, but not single, procedures requiring
general anaesthesia before age 3 yr is associated with a specific pattern of deficits in …

Introduction: Immature animals exposed to anesthesia display apoptotic neurodegeneration
and neurobehavioral deficits. The safety of anesthetic agents in children has been evaluated …

Importance Exposure of young animals to commonly used anesthetics causes neurotoxicity
including impaired neurocognitive function and abnormal behavior. The potential …

Experimental evidence of anesthesia-induced neurotoxicity has caused serious concern
about the long-term effect of commonly used volatile anesthetic agents on young children …

Neurodegeneration has been reported in young animals after exposure to all commonly
used general anesthetic agents. The brain may be particularly vulnerable to anesthetic …

Background Most common anesthetic agents have been implicated in causing
neurodegeneration in the developing animal brain, leading to warnings regarding their use …

Importance Clinical studies of neurodevelopmental outcomes after anesthetic exposure
have evaluated a range of outcomes with mixed results. Objective To examine via meta …