Gut microbiota may contribute to the postnatal male reproductive abnormalities induced by prenatal dibutyl phthalate exposure

T Zhang, X Zhou, X Zhang, X Ren, J Wu, Z Wang… - Chemosphere, 2022 - Elsevier
Phthalate is an environmental endocrine disruptor that causes direct and intergenerational
male reproductive damage. However, its mechanisms require further investigation. The role …

Di‐(2‐ethylhexyl) phthalate exposure induces female reproductive toxicity and alters the intestinal microbiota community structure and fecal metabolite profile in mice

X Fu, H Han, Y Li, B Xu, W Dai, Y Zhang… - Environmental …, 2021 - Wiley Online Library
Abstract Di‐(2‐ethylhexyl) phthalate (DEHP) is one of the most commonly used plasticizers,
and it is widely applied in various plastic products. DEHP is an endocrine‐disrupting …

Gut microbiota dysbiosis might be responsible to different toxicity caused by Di-(2-ethylhexyl) phthalate exposure in murine rodents

G Wang, Q Chen, P Tian, L Wang, X Li, Y Lee… - Environmental …, 2020 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer, which can enter
the body through a variety of ways and exerted multiple harmful effects, including liver …

An insight into the critical role of gut microbiota in triggering the phthalate-induced toxicity and its mitigation using probiotics

SP Goyal, C Saravanan - Science of The Total Environment, 2023 - Elsevier
Exposure to phthalates, a major food safety concern, has been implicated in various chronic
human disorders. As dietary exposure serves as a primary exposure route for phthalate …

[HTML][HTML] Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice

R Almamoun, P Pierozan, L Manoharan… - … and Environmental Safety, 2023 - Elsevier
Di-n-butyl phthalate (DBP) is a ubiquitous environmental contaminant linked with various
adverse health effects, including immune system dysfunction. Gut microbial dysbiosis can …

[HTML][HTML] Effects of Bisphenol A on reproductive toxicity and gut microbiota dysbiosis in male rats

R Liu, D Cai, X Li, B Liu, J Chen, X Jiang, H Li… - Ecotoxicology and …, 2022 - Elsevier
Bisphenol A (BPA) is an environmental endocrine disruptor. Recent studies have shown an
association between decreased spermatogenesis and gut microbiota alteration. However …

Single-cell transcriptomic profiling to evaluate the effects of Di (2-ethylhexyl) phthalate exposure on early meiosis of female mouse germ cells

Y Tian, Y Zhang, PY Dong, YH Sun, AH Zhao, W Shen… - Chemosphere, 2022 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) has proven characteristics of an endocrine-
disrupting compound (EDC), which can threaten the reproductive health of humans and …

[HTML][HTML] Lactobacillus plantarum TW1-1 Alleviates Diethylhexylphthalate-Induced Testicular Damage in Mice by Modulating Gut Microbiota and Decreasing …

X Tian, Z Yu, P Feng, Z Ye, R Li, J Liu, J Hu… - Frontiers in cellular …, 2019 - frontiersin.org
Diethylhexylphthalate (DEHP), acting as an endocrine disruptor, disturbed reproductive
health. Here, we evaluated the effects of Lactobacillus plantarum TW1-1 (L. plantarum TW1 …

Lactic acid bacteria alleviate di-(2-ethylhexyl) phthalate-induced liver and testis toxicity via their bio-binding capacity, antioxidant capacity and regulation of the gut …

Q Chen, Q Kong, P Tian, Y He, J Zhao, H Zhang… - Environmental …, 2022 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a plasticiser that, if absorbed into the human
body, can cause various adverse effects including reproductive toxicity, liver toxicity and gut …

Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice

M Lei, R Menon, S Manteiga, N Alden, C Hunt… - Msystems, 2019 - Am Soc Microbiol
Exposure to environmental chemicals during windows of development is a potentially
contributing factor in gut microbiota dysbiosis and linked to chronic diseases and …