Increasing evidence suggests that the pathogenesis of chronic obstructive pulmonary
disease (COPD) is associated with FUN14 domain protein 1 (FUNDC1)-mediated …

Chronic obstructive pulmonary disease (COPD) is a major global epidemic with increasing
incidence worldwide. The pathogenesis of COPD is involved with mitochondrial autophagy …

Recent studies demonstrate that the autophagy-dependent turnover of mitochondria
(mitophagy) mediates pulmonary epithelial cell death in response to cigarette smoke extract …

Cigarette smoke (CS)-induced mitochondrial damage with increased reactive oxygen
species (ROS) production has been implicated in COPD pathogenesis by accelerating …

Objective Herein, inhibition of hepatocyte growth factor receptor, c-Met, significantly
increased cytochrome c release and Bax/Bcl-2 ratio, indicating that c-Met played an anti …

Background Idiopathic pulmonary fibrosis (IPF) is a fatal respiratory disease without effective
treatments. Mitochondrial dysfunction weakens the ability of mesenchymal stem cells …

Quercetin, an important dietary flavonoid has been demonstrated to potentially reverse or
even prevent pulmonary arterial hypertension (PAH) progression. However, the effects of …

Plumbagin (PL) is a natural naphthoquinone compound, isolated from Plumbago zeylanica
that has cytotoxic and antimigratory potential in many cancer. However, the cytotoxic …

Endoplasmic reticulum stress (ERS)‐induced apoptosis of airway epithelial cells plays an
important role in the pathogenesis of chronic obstructive pulmonary disease (COPD) …

The objective of the present study was to determine the anticancer effects of cedrol in A549
human non-small cell lung cancer cells by examining the effects of cedrol on apoptosis …