Age differences in brain signal variability are robust to multiple vascular controls
A host of studies support that younger, better performing adults express greater moment-to-
moment blood oxygen level-dependent (BOLD) signal variability (SDBOLD) in various …
moment blood oxygen level-dependent (BOLD) signal variability (SDBOLD) in various …
Resting state BOLD variability is linked to white matter vascular burden in healthy aging but not in older adults with subjective cognitive decline
V Scarapicchia, M Garcia-Barrera… - Frontiers in human …, 2019 - frontiersin.org
Background: Alzheimer's disease (AD) is the leading cause of dementia. A lack of curative
treatments and a rapidly aging global population have amplified the need for early …
treatments and a rapidly aging global population have amplified the need for early …
The effects of age on resting‐state BOLD signal variability is explained by cardiovascular and cerebrovascular factors
Accurate identification of brain function is necessary to understand neurocognitive aging,
and thereby promote health and well‐being. Many studies of neurocognitive aging have …
and thereby promote health and well‐being. Many studies of neurocognitive aging have …
Differential age effects on cerebral blood flow and BOLD response to encoding: associations with cognition and stroke risk
Changes in the cerebrovascular system due to age or disease can significantly alter the
blood-oxygenation-level-dependent (BOLD) signal and complicate its interpretation. The …
blood-oxygenation-level-dependent (BOLD) signal and complicate its interpretation. The …
BOLD neurovascular coupling does not change significantly with normal aging
Studies of cognitive function that compare the blood oxygenation level dependent (BOLD)
signal across age groups often require the assumption that neurovascular coupling does not …
signal across age groups often require the assumption that neurovascular coupling does not …
Increasing measurement accuracy of age‐related BOLD signal change: Minimizing vascular contributions by resting‐state‐fluctuation‐of‐amplitude scaling
In this report we demonstrate a hemodynamic scaling method with resting‐state fluctuation
of amplitude (RSFA) in healthy adult younger and older subject groups. We show that RSFA …
of amplitude (RSFA) in healthy adult younger and older subject groups. We show that RSFA …
Moderating effect of cortical thickness on BOLD signal variability age-related changes
DR Pur, RA Eagleson, A de Ribaupierre… - Frontiers in aging …, 2019 - frontiersin.org
The time course of neuroanatomical structural and functional measures across the lifespan
is commonly reported in association with aging. Blood oxygen-level dependent signal …
is commonly reported in association with aging. Blood oxygen-level dependent signal …
Lost dynamics and the dynamics of loss: longitudinal compression of brain signal variability is coupled with declines in functional integration and cognitive …
DD Garrett, A Skowron, S Wiegert, J Adolf… - Cerebral …, 2021 - academic.oup.com
Reduced moment-to-moment blood oxygen level-dependent (BOLD) signal variability has
been consistently linked to advanced age and poorer cognitive performance, showing …
been consistently linked to advanced age and poorer cognitive performance, showing …
BOLD hemodynamic response function changes significantly with healthy aging
Functional magnetic resonance imaging (fMRI) has been used to infer age-differences in
neural activity from the hemodynamic response function (HRF) that characterizes the blood …
neural activity from the hemodynamic response function (HRF) that characterizes the blood …
Dynamic and static contributions of the cerebrovasculature to the resting-state BOLD signal
Functional magnetic resonance imaging (fMRI) in the resting state, particularly fMRI based
on the blood-oxygenation level-dependent (BOLD) signal, has been extensively used to …
on the blood-oxygenation level-dependent (BOLD) signal, has been extensively used to …