Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Opportunities for plant natural products in infection control

AM Salam, CL Quave - Current opinion in microbiology, 2018 - Elsevier
The continued spread of antimicrobial resistance represents one of the most serious
infectious disease threats to global health. There is consensus that a key component of …

Plant secondary metabolites in the battle of drugs and drug-resistant bacteria: new heroes or worse clones of antibiotics?

CL Gorlenko, HY Kiselev, EV Budanova… - Antibiotics, 2020 - mdpi.com
Infectious diseases that are caused by bacteria are an important cause of mortality and
morbidity in all regions of the world. Bacterial drug resistance has grown in the last decades …

Recent advances in the discovery of plant-derived antimicrobial natural products to combat antimicrobial resistant pathogens: insights from 2018–2022

S Woo, L Marquez, WJ Crandall, CJ Risener… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2018 to 2022 Antimicrobial resistance (AMR) poses a significant global health
threat. There is a rising demand for innovative drug scaffolds and new targets to combat …

A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery

U Anand, N Jacobo-Herrera, A Altemimi, N Lakhssassi - Metabolites, 2019 - mdpi.com
The war on multidrug resistance (MDR) has resulted in the greatest loss to the world's
economy. Antibiotics, the bedrock, and wonder drug of the 20th century have played a …

Back to Nature: Medicinal plants as promising sources for antibacterial drugs in the post-antibiotic era

EM Abdallah, BY Alhatlani, R de Paula Menezes… - Plants, 2023 - mdpi.com
Undoubtedly, the advent of antibiotics in the 19th century had a substantial impact,
increasing human life expectancy. However, a multitude of scientific investigations now …

Secondary plant metabolites as potent drug candidates against antimicrobial-resistant pathogens

K Keita, C Darkoh, F Okafor - SN Applied Sciences, 2022 - Springer
Antibiotic resistance is a major public health threat of the twenty-first century and represents
an important risk to the global economy. Healthcare-associated infections mainly caused by …

Natural products as antibacterial agents

GB Mahady, Y Huang, BJ Doyle, T Locklear - Studies in natural products …, 2008 - Elsevier
For thousands of years medicinal plants have played a significant role in the treatment of a
wide range of medical conditions, including infectious diseases. Some naturally occurring …

Phytochemicals: a promising weapon in the arsenal against antibiotic-resistant bacteria

B Khameneh, NAM Eskin, M Iranshahy… - Antibiotics, 2021 - mdpi.com
The extensive usage of antibiotics and the rapid emergence of antimicrobial-resistant
microbes (AMR) are becoming important global public health issues. Many solutions to …

Natural extracts for antibacterial applications

C Chen, L Chen, C Mao, L Jin, S Wu, Y Zheng, Z Cui… - Small, 2024 - Wiley Online Library
Bacteria‐induced epidemics and infectious diseases are seriously threatening the health of
people around the world. In addition, antibiotic therapy has been inducing increasingly more …