Lesions of the nucleus basalis magnocellularis (Meynert) induce enhanced somatosensory responses and tactile hypersensitivity in rats

S Dezawa, K Nagasaka, Y Watanabe… - Experimental …, 2021 - Elsevier
We used the immunotoxin 192 immunoglobulin G-saporin to produce a selective cholinergic
lesion in the nucleus basalis of Meynert (NBM) of rats and investigated whether the NBM …

Electrophysiological and pharmacological properties of nucleus basalis magnocellularis neurons in rats.

Y Zhang, SG Lü, Y Ji, ZQ Zhao, J Mei - Acta pharmacologica Sinica, 2004 - europepmc.org
Aim To investigate the primary electrophysiological and pharmacological properties of the
nucleus basalis magnocellularis (nbM) neurons. Methods Single unit extracellular …

Physiologic effects of nucleus basalis magnocellularis stimulation on rat barrel cortex neurons

MA Howard, DJ Simons - Experimental brain research, 1994 - Springer
Cholinergic neurons in the nucleus basalis magnocellularis (NBM) project to the cerebral
cortex and are thought to play an important role in learning and memory, and other cognitive …

Selective immunolesioning of the basal forebrain cholinergic neurons in rats: effect on attention using the 5-choice serial reaction time task

V Risbrough, B Bontempi, F Menzaghi - Psychopharmacology, 2002 - Springer
Rationale. Excitotoxic lesions of the nucleus basalis magnocellularis (nbm) in rats produce
deficits in performance of the 5-choice serial reaction time (5CSRT) task, suggesting that …

Ibotenic acid lesion of nucleus basalis magnocellularis differentially affects cholinergic, glutamatergic and GABAergic markers in cortical rat brain regions

S Roβner, R Schliebs, V Bigl - Brain research, 1994 - Elsevier
The present study was undertaken to study the effect of reduced cortical cholinergic activity
on γ-aminobutyric acid (GABA) ergic and glutamatergic mechanisms in cholinoceptive …

Comparison of behavioral effects of nucleus basalis magnocellularis lesions and somatosensory cortex ablation in the rat

DF Wozniak, GR Stewart, S Finger, JW Olney - Neuroscience, 1989 - Elsevier
Cholinergic neurons in the nucleus basalis region of the forebrain project to various portions
of the cerebral cortex, including somatosensory cortex. Degeneration of these neurons and …

Cognitive effects of neurotoxic lesions of the nucleus basalis magnocellularis in rats: differential roles for corticopetal versus amygdalopetal projections

RJ Beninger, HC Dringenberg, RJ Boegman… - Neurotoxicity …, 2001 - Springer
The cholinergic hypothesis states that cholinergic neurons of the basal forebrain nucleus
basalis magnocellularis (nbm) that project to cortical and amy-gdalar targets play an …

Regulation of cortical blood flow responses by the nucleus basalis of Meynert during nociceptive processing

T Paquette, R Tokunaga, S Touj, H Leblond… - Neuroscience …, 2019 - Elsevier
Cerebral blood flow (CBF) is essential for neuronal metabolic functions. CBF is partly
regulated by cholinergic projections from the nucleus basalis of Meynert (NBM) during …

Topographical projections from the nucleus basalis magnocellularis (Meynert) to the frontal cortex: A voltage-sensitive dye imaging study in rats

K Nagasaka, Y Watanabe, I Takashima - Brain Stimulation, 2017 - Elsevier
Background The nucleus basalis magnocellularis/Meynert (NBM) has been explored as a
new target for deep brain stimulation for neurological disorders. Although anatomical studies …

Selective cholinergic lesions in the rat nucleus basalis magnocellularis with limited damage in the medial septum specifically alter attention performance in the five …

H Harati, A Barbelivien, B Cosquer, M Majchrzak… - Neuroscience, 2008 - Elsevier
Selective immunotoxic cholinergic lesions in the nucleus basalis magnocellularis (NBM)
impair visuospatial attention performance in a 5-choice serial reaction time task (5-CSRT …