While mechanosensitive ion channels' gating has been well documented, the effect of
membrane mechanics, in particular membrane curvature, on the function of transporters …

ABC transporters utilize ATP for export processes to provide cellular resistance against
toxins, antibiotics, and harmful metabolites in eukaryotes and prokaryotes. Based on static …

Sav1866, a bacterial ATP-binding cassette (ABC) exporter, plays a crucial role in cellular
processes by facilitating the efflux of a diverse range of substrates, including drugs …

ABC exporters are highly dynamic membrane proteins that span a huge spectrum of
different conformations. A detailed integrated approach of cellular, biochemical and …

Membrane proteins are currently investigated after detergent extraction from native cellular
membranes and reconstitution into artificial liposomes or nanodiscs, thereby removing them …

High-resolution structure determination of membrane proteins typically requires isolation
from the native lipid bilayer and reconstitution into artificial membrane mimics. For this …

ATP-binding cassette (ABC) transporters play crucial roles in cellular processes, such as
nutrient uptake, drug resistance, cell-volume regulation and others. Despite their …

The ATP-binding cassette (ABC) transporter associated with antigen processing (TAP)
participates in immune surveillance by moving proteasomal products into the endoplasmic …

High-resolution structure determination of membrane proteins typically requires isolation
from the native lipid bilayer and reconstitution into artificial membrane mimics. For this …

ATP-binding cassette (ABC) transporters constitute one of the largest protein superfamilies,
and they mediate the transport of diverse substrates across the membrane. The molecular …