Phospholipases B1, B2, C and D of Candida albicans play a significant role in the host
invasive process. Hence we evaluated the in vitro expression of PLB1, PLB2, PLC1 and …

Phospholipases have been proposed to contribute to the virulence of Candida albicans.
Recently, a candidal strain deleted for PLB1, the gene encoding the predominant …

Candida is the fourth most common organism responsible for bloodstream infections in
many intensive care units, with Candida albicans being the most predominant species …

The extracellular phospholipases of Candida albicans are considered to play a significant
role in the pathogenesis of human infections. Therefore 30 clinical isolates of C. albicans …

Phospholipases are critical for modification and redistribution of lipid substrates, membrane
remodeling and microbial virulence. Among the many different classes of phospholipases …

The phosphatidylcholine-specific phospholipase D1 (PLD1) in Saccharomyces cerevisiae is
involved in vesicle transport and is essential for sporulation. The gene encoding the …

The Candida albicans PLB1gene was cloned using a polymerase chain reaction-based
approach relying on degenerate oligonucleotide primers designed according to the amino …

Phospholipase D1 (PLD1) mutants of Candida albicans are defective in important in vivo
and in vitro virulence factors. PLD1 mutants colonize the murine alimentary tract as well as …

Microbial pathogens use a number of genetic strategies to invade the host and cause
infection. These common themes are found throughout microbial systems. Secretion of …

Degenerate oligonucleotides (derived from conserved regions of PLB1 genes from S.
cerevisiae and other fungi) were used to amplify PLB1 homolog fragments from C. albicans …