The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development
SBV Ramos, DJ Stumpo, EA Kennington, RS Phillips… - 2004 - journals.biologists.com
The CCCH tandem zinc finger protein, Zfp36l2, like its better-known relative tristetraprolin
(TTP), can decrease the stability of AU-rich element-containing transcripts in cell transfection …
(TTP), can decrease the stability of AU-rich element-containing transcripts in cell transfection …
Zfp36l3, a Rodent X Chromosome Gene Encoding a Placenta-Specific Member of the Tristetraprolin Family of CCCH Tandem Zinc Finger Proteins
PJ Blackshear, RS Phillips, S Ghosh… - Biology of …, 2005 - academic.oup.com
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger (TZF) proteins can
bind directly to AU-rich elements (ARE) in mRNA, causing deadenylation and destabilization …
bind directly to AU-rich elements (ARE) in mRNA, causing deadenylation and destabilization …
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis
DJ Stumpo, HE Broxmeyer, T Ward… - Blood, The Journal …, 2009 - ashpublications.org
Members of the tristetraprolin family of tandem CCCH finger proteins can bind to AU-rich
elements in the 3′-untranslated region of mRNAs, leading to their deadenylation and …
elements in the 3′-untranslated region of mRNAs, leading to their deadenylation and …
Chorioallantoic Fusion Defects and Embryonic Lethality Resulting from Disruption of Zfp36L1, a Gene Encoding a CCCH Tandem Zinc Finger Protein of the …
DJ Stumpo, NA Byrd, RS Phillips, S Ghosh… - … and cellular biology, 2004 - Taylor & Francis
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
The mRNA-destabilizing protein Tristetraprolin targets “meiosis arrester” Nppc mRNA in mammalian preovulatory follicles
G Xi, L An, W Wang, J Hao, Q Yang… - Proceedings of the …, 2021 - National Acad Sciences
C-natriuretic peptide (CNP) and its receptor guanylyl cyclase, natriuretic peptide receptor 2
(NPR2), are key regulators of cyclic guanosine monophosphate (cGMP) homeostasis. The …
(NPR2), are key regulators of cyclic guanosine monophosphate (cGMP) homeostasis. The …
Phylogenetic distribution and evolution of the linked RNA-binding and NOT1-binding domains in the tristetraprolin family of tandem CCCH zinc finger proteins
PJ Blackshear, L Perera - Journal of Interferon & Cytokine Research, 2014 - liebertpub.com
In humans, the tristetraprolin or TTP family of CCCH tandem zinc finger (TZF) proteins
comprises 3 members, encoded by the genes ZFP36, ZFP36L1, and ZFP36L2. These …
comprises 3 members, encoded by the genes ZFP36, ZFP36L1, and ZFP36L2. These …
The RNA-binding protein, ZFP36L2, influences ovulation and oocyte maturation
CB Ball, KF Rodriguez, DJ Stumpo, F Ribeiro-Neto… - PloS one, 2014 - journals.plos.org
ZFP36L2 protein destabilizes AU-rich element-containing transcripts and has been
implicated in female fertility. In the C57BL/6NTac mouse, a mutation in Zfp36l2 that results in …
implicated in female fertility. In the C57BL/6NTac mouse, a mutation in Zfp36l2 that results in …
Interactions of CCCH zinc finger proteins with mRNA: binding of tristetraprolin-related zinc finger proteins to AU-rich elements and destabilization of mRNA
WS Lai, E Carballo, JM Thorn, EA Kennington… - Journal of Biological …, 2000 - ASBMB
Macrophages derived from tristetraprolin (TTP)-deficient mice exhibited increased tumor
necrosis factor α (TNFα) release as a consequence of increased stability of TNFα mRNA …
necrosis factor α (TNFα) release as a consequence of increased stability of TNFα mRNA …
Identification of four CCCH zinc finger proteins in Xenopus, including a novel vertebrate protein with four zinc fingers and severely restricted expression
J De, WS Lai, JM Thorn, SM Goldsworthy, X Liu… - Gene, 1999 - Elsevier
Tristetraprolin (TTP), the prototype of a class of CCCH zinc finger proteins, is a
phosphoprotein that is rapidly and transiently induced by growth factors and serum in …
phosphoprotein that is rapidly and transiently induced by growth factors and serum in …
Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements
The zinc finger protein tristetraprolin (TTP) promotes translation repression and degradation
of mRNAs containing AU-rich elements (AREs). Although much attention has been directed …
of mRNAs containing AU-rich elements (AREs). Although much attention has been directed …