The endocannabinoid (eCB) system has attracted attention for its role in various behavioral
and brain functions, and as a therapeutic target in neuropsychiatric disease states, including …

The term cannabinoids encompasses compounds produced by the plant Cannabis sativa,
such as Δ 9-tetrahydrocannabinol, and synthetic counterparts. Their actions occur mainly …

Cannabis has been used for hundreds of years, with its ability to dampen feelings of anxiety
often reported as a primary reason for use. Only recently has the specific role cannabinoids …

The endocannabinoid (eCB) system is one the most ubiquitous signaling systems of the
brain and offers a rich pharmacology including multiple druggable targets. Preclinical …

The endocannabinoid system plays an important role in the control of emotions, and its
dysregulation has been implicated in several psychiatric disorders. The most common self …

Recent studies have demonstrated anxiolytic potential of pharmacological endocannabinoid
(eCB) augmentation approaches in a variety of preclinical models. Pharmacological …

The endocannabinoid system has recently emerged as a promising therapeutic target for the
treatment of stress-related emotional disorders. A growing literature base has collectively …

Objective: The present review provides a brief introduction into the endocannabinoid system
and discusses main strategies of pharmacological interventions. Method: We have reviewed …

Two topics are presented in this review. In the first section, we review data regarding the
effects of the endocannabinoids (eCBs) and cannabinoid receptors on neuroimmune …

Cannabinoid receptors and their endogenous ligands are located throughout the limbic, or
“emotional,” brain, where they modulate synaptic neurotransmission. Converging preclinical …