Metabolic Profiling Early Post-Allogeneic Haematopoietic Cell Transplantation in the Context of CMV Infection

KK Rasmussen, Q Dos Santos, CR MacPherson… - Metabolites, 2023 - mdpi.com
Immune dysfunction resulting from allogeneic haematopoietic stem cell transplantation
(aHSCT) predisposes one to an elevated risk of cytomegalovirus (CMV) infection. Changes …

Validation of a plasma metabolomics model that allows anticipation of the occurrence of cytomegalovirus DNAaemia in allogeneic stem cell transplant recipients

D Monleón, A Talaya, E Giménez… - Journal of Medical …, 2018 - microbiologyresearch.org
A plasma metabolomic model obtained by means of untargeted 1H nuclear magnetic
resonance, to which taurine, choline, methylamine, total glutathione, trimethylamine N-oxide …

Plasma metabolomics profiling for the prediction of cytomegalovirus DNAemia and analysis of virus–host interaction in allogeneic stem cell transplant recipients

D Monleon, E Gimenez… - Journal of General …, 2015 - microbiologyresearch.org
Metabolomics analysis of biofluids is increasingly being recognized as a useful tool for the
diagnosis and management of a number of infectious diseases. Here we showed that …

[HTML][HTML] Global metabolomics in allogeneic hematopoietic cell transplantation recipients discordant for chronic graft-versus-host disease

DL Kelly, N Farhadfar, A Starkweather… - Biology of Blood and …, 2020 - Elsevier
Chronic graft-versus-host disease (cGVHD) remains a significant late effect issue for
allogeneic hematopoietic cell transplantation (allo-HCT) survivors, contributing to morbidity …

Deep functional immunophenotyping predicts risk of cytomegalovirus reactivation after hematopoietic cell transplantation

JF Camargo, ED Wieder, E Kimble… - Blood, The Journal …, 2019 - ashpublications.org
Cytomegalovirus (CMV) is the most common viral infection in hematopoietic cell
transplantation (HCT) recipients. We performed deep phenotyping of CMV-specific T cells to …

[HTML][HTML] Pretransplant systemic metabolic profiles in allogeneic hematopoietic stem cell transplant recipients-identification of patient subsets with increased transplant …

H Reikvam, Ø Bruserud, KJ Hatfield - Transplantation and Cellular Therapy, 2023 - Elsevier
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is used in the treatment of
high-risk acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS); however …

A preliminary investigation towards the risk stratification of allogeneic stem cell recipients with respect to the potential for development of GVHD via their pre-transplant …

D Contaifer Jr, CH Roberts, NG Kumar, R Natarajan… - Cancers, 2019 - mdpi.com
The clinical outcome of allogeneic hematopoietic stem cell transplantation (SCT) may be
influenced by the metabolic status of the recipient following conditioning, which in turn may …

Kinetics of inflammatory biomarkers in plasma predict the occurrence and features of cytomegalovirus DNAemia episodes in allogeneic hematopoietic stem cell …

A Talaya, E Giménez, V Vinuesa, A Pérez… - Medical Microbiology …, 2019 - Springer
Cytomegalovirus (CMV) DNAemia occurs frequently in CMV-seropositive allogeneic
hematopoietic stem cell transplant (allo-HSCT) recipients, and usually results from …

Altered lipid metabolism in patients with acute graft-versus-host disease after allogeneic hematopoietic cell transplantation

M Tyszka, D Maciejewska-Markiewicz, D Styburski… - Leukemia Research, 2024 - Elsevier
Allogeneic hematopoietic cell transplantation (allo-HCT) remains the sole curative option for
many hematological malignancies and other diseases. Nevertheless, its application is …

The pretransplant systemic metabolic profile reflects a risk of acute graft versus host disease after allogeneic stem cell transplantation

H Reikvam, K Hatfield, Ø Bruserud - Metabolomics, 2016 - Springer
Allogeneic stem cell transplantation is used in the treatment of younger patients with severe
hematological diseases, especially hematological malignancies, and acute graft versus host …