The brain demonstrates remarkable adaptability during early development, responding to
internal and external stimuli through plasticity. Different sensory systems undergo critical …

Within primary visual cortex (V1), brain‐derived neurotrophic factor (BDNF) signaling
through its high‐affinity receptor TrkB is important for normal development and experience …

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family, which has
been reported to regulate neurogenesis in the dentate gyrus, but the molecular control over …

Sensory experience refines neuronal structure and functionality. The visual system has
proved to be a productive model system to study this plasticity. In the neonatal retina, the …

The sensitivity of the nervous system to receive and respond to events, both internal and in
the environment, depends on the ability of neural structures to remodel in response to …

Brain plasticity, in its simplest definition, is the ability of brain to change itself. This
phenomenon, which is important for the development and wiring of neuronal networks, is …

In the central nervous system (CNS), the expression of molecules is strictly regulated during
development. Control of the spatiotemporal expression of molecules is a mechanism not …

Binding of the neurotrophin brain-derived neurotrophic factor (BDNF) to the TrkB receptor is
a major survival mechanism during embryonic development. In the aged brain, however …

The work of the Maffei lab, and that of other groups, has revealed the critical role of the
activity-dependent synthesis and release of neurotrophic factors in the formation, maturation …

Elevated states of brain plasticity typical for critical periods of early postnatal life can be
reinstated in the adult brain through interventions, such as antidepressant treatment and …