[HTML][HTML] The treatment of Advanced Melanoma: Current approaches and new challenges

A Boutros, E Croce, M Ferrari, R Gili, G Massaro… - Critical Reviews in …, 2024 - Elsevier
In recent years, advances in melanoma treatment have renewed patient hope. This
comprehensive review emphasizes the evolving treatment landscape, particularly …

Long-term survival as a treatment benchmark in melanoma: latest results and clinical implications

KF Grossmann, K Margolin - Therapeutic advances in …, 2015 - journals.sagepub.com
Historically, stage III–IV melanoma patients have had few options to achieve long-term
survival. For patients with stage III disease, surgery alone may be curative for approximately …

Advanced stage melanoma therapies: detailing the present and exploring the future

C Luther, U Swami, J Zhang, M Milhem… - Critical reviews in …, 2019 - Elsevier
Metastatic melanoma therapies have proliferated over the last ten years. Prior to this,
decades passed with only very few drugs available to offer our patients, and even then …

Current management of advanced melanoma: a transformed landscape

DE Gyorki, J Spillane, D Speakman… - ANZ journal of …, 2014 - Wiley Online Library
The prognosis for patients with stage IV melanoma has historically been extremely poor and
there have until recently been no effective treatment options. The last 3 years have seen a …

Gaining momentum: New options and opportunities for the treatment of advanced melanoma

O Michielin, C Hoeller - Cancer treatment reviews, 2015 - Elsevier
Before 2011, patients with advanced or metastatic melanoma had a particularly poor long-
term prognosis. Since traditional treatments failed to confer a survival benefit, patients were …

[HTML][HTML] A systematic literature review and network meta-analysis of effectiveness and safety outcomes in advanced melanoma

MG Franken, B Leeneman, M Gheorghe… - European Journal of …, 2019 - Elsevier
Background Although a myriad of novel treatments entered the treatment paradigm for
advanced melanoma, there is lack of head-to-head evidence. We conducted a network meta …

[HTML][HTML] Activity and safety of first-line treatments for advanced melanoma: a network meta-analysis

A Boutros, ET Tanda, E Croce, F Catalano… - European Journal of …, 2023 - Elsevier
Background Treatment options for advanced melanoma have increased with the US Food
and Drug Administration approval of the anti-LAG3 plus anti-PD-1 relatlimab/nivolumab …

[HTML][HTML] Treatment of advanced melanoma in 2020 and beyond

RW Jenkins, DE Fisher - Journal of Investigative Dermatology, 2021 - Elsevier
The melanoma field has seen an unprecedented set of clinical advances over the past
decade. Therapeutic efficacy for advanced or metastatic melanoma went from being one of …

Three decades of evolving treatment for melanoma: No improvement in survival?

SE Young, AE Giuliano, DL Morton - Journal of Clinical Oncology, 2005 - ascopubs.org
7511 Background: Despite tremendous effort towards the development of novel treatments
for advanced melanoma, a significant survival benefit has not been clearly documented. The …

Melanoma: an update on systemic therapies

L Skudalski, R Waldman, PE Kerr… - Journal of the American …, 2022 - Elsevier
Despite advances in early detection as described in part 1 of this continuing medical
education series, melanoma continues to be a large contributor to cutaneous cancer-related …