We successfully produced two human β-defensins (hBD-1 and hBD-2) in bacteria as
functional peptides and tested their antibacterial activities against Salmonella enterica …

In this work, taking human β‐defensin‐2 (HBD2) as a demonstrative molecule, the strategies
for high efficient production of functional human β‐defensins in E. coli were studied. Fusion …

Five variants of human β-defensins (HBDs) were expressed in Escherichia coli using two
vector systems (pET28a (+) and pQE30) with inducible expression by IPTG. The last vector …

Human β-defensin 2 (hBD-2) is a 41-amino acid cationic peptide of the innate immune
system that serves as antimicrobial molecule. We determined the bactericidal activity of …

Human β-defensins (HBDs) are cationic antimicrobial peptides that are components of the
innate immune system. They are characterized by three disulfide bridges. However, the …

The antimicrobial activity of human β-defensin 3 (hBD-3) against multidrug-resistant clinical
isolates of Staphylococcus aureus, Enterococcus faecium, Pseudomonas aeruginosa …

ABSTRACT Human β-defensin 3 (hBD3) is a highly basic 45-amino-acid protein that acts
both as an antimicrobial agent and as a chemoattractant molecule. Although the nature of its …

Despite partial sequence identity and structural similarity, human β-defensin 3 (HBD3) kills
Staphylococcus aureus with a 4-to 8-fold higher efficiency than human β-defensin 2 (HBD2) …

Human beta-defensin-2 (hBD-2), a small cationic peptide, exhibits a broad range of
antimicrobial activity. It has been found to play important roles in innate and adaptive …

ABSTRACT β‐Defensins are antibiotic peptides involved in host defense at the epithelial
surface. Three human β‐defensins (hBDs)‐‐hBD‐1, hBD‐2, and hBD‐3‐‐have been …