Nicotine-induced ILF2 facilitates nuclear mRNA export of pluripotency factors to promote stemness and chemoresistance in human esophageal cancer
Y Li, M Wang, M Yang, Y Xiao, Y Jian, D Shi, X Chen… - Cancer Research, 2021 - AACR
Balancing mRNA nuclear export kinetics with its nuclear decay is critical for mRNA
homeostasis control. How this equilibrium is aberrantly disrupted in esophageal cancer to …
homeostasis control. How this equilibrium is aberrantly disrupted in esophageal cancer to …
Mitophagy bridges DNA sensing with metabolic adaption to expand lung cancer stem‐like cells
Z Liu, S Shan, Z Yuan, F Wu, M Zheng, Y Wang… - EMBO …, 2023 - embopress.org
While previous studies have identified cancer stem‐like cells (CSCs) as a crucial driver for
chemoresistance and tumor recurrence, the underlying mechanisms for populating the CSC …
chemoresistance and tumor recurrence, the underlying mechanisms for populating the CSC …
HnRNPA2B1 ISGylation Regulates m6A‐Tagged mRNA Selective Export via ALYREF/NXF1 Complex to Foster Breast Cancer Development
T Jin, L Yang, C Chang, H Luo, R Wang… - Advanced …, 2024 - Wiley Online Library
Regulating nuclear export precisely is essential for maintaining mRNA homeostasis and
impacts tumor progression. However, the mechanisms governing nuclear mRNA export …
impacts tumor progression. However, the mechanisms governing nuclear mRNA export …
Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling
L Wang, L Du, X Xiong, Y Lin, J Zhu, Z Yao, S Wang… - Oncogene, 2021 - nature.com
Smoking is one of the most impactful lifestyle-related risk factors in many cancer types
including esophageal squamous cell carcinoma (ESCC). As the major component of …
including esophageal squamous cell carcinoma (ESCC). As the major component of …
Nicotine upregulates microRNA-21 and promotes TGF-β-dependent epithelial-mesenchymal transition of esophageal cancer cells
Y Zhang, T Pan, X Zhong, C Cheng - Tumor Biology, 2014 - Springer
A consistent positive association between cigarette smoking and the human esophageal
cancer has been confirmed all over the world. However, details in the association need to be …
cancer has been confirmed all over the world. However, details in the association need to be …
[HTML][HTML] linc01305 promotes metastasis and proliferation of esophageal squamous cell carcinoma through interacting with IGF2BP2 and IGF2BP3 to stabilize HTR3A …
GW Huang, QQ Chen, CC Ma, LH Xie, J Gu - The International Journal of …, 2021 - Elsevier
Evidence shows that long noncoding RNAs (lncRNAs) modulate mRNAs of multiple genes
by post-transcriptional regulation. However, in esophageal squamous cell carcinoma …
by post-transcriptional regulation. However, in esophageal squamous cell carcinoma …
Nrf2 promotes esophageal squamous cell carcinoma (ESCC) resistance to radiotherapy through the CaMKIIα-associated activation of autophagy
D Xia, XR Zhang, YL Ma, ZJ Zhao, R Zhao, YY Wang - Cell & bioscience, 2020 - Springer
Background NF-E2-related factor 2 (Nrf2) is involved in the radiation resistance of
esophageal squamous cell carcinoma (ESCC), but the underlying molecular mechanism is …
esophageal squamous cell carcinoma (ESCC), but the underlying molecular mechanism is …
FTO-mediated autophagy inhibition promotes non-small cell lung cancer progression by reducing the stability of SESN2 mRNA
K Wang, Z Mei, M Zheng, X Liu, D Li, H Wang - Heliyon, 2024 - cell.com
The role of fat mass and obesity-associated protein (FTO), an N 6-methyladenosine (m 6 A)
demethylase, in non-small cell lung cancer (NSCLC) has recently received widespread …
demethylase, in non-small cell lung cancer (NSCLC) has recently received widespread …
[PDF][PDF] SIDT2 RNA transporter promotes lung and gastrointestinal tumor development
TA Nguyen, KT Bieging-Rolett, TL Putoczki, IP Wicks… - Iscience, 2019 - cell.com
RNautophagy is a newly described type of selective autophagy whereby cellular RNAs are
transported into lysosomes for degradation. This process involves the transmembrane …
transported into lysosomes for degradation. This process involves the transmembrane …
CLU (clusterin) promotes mitophagic degradation of MSX2 through an AKT-DNM1L/Drp1 axis to maintain SOX2-mediated stemness in oral cancer stem cells
Mitophagy regulates cancer stem cell (CSC) populations affecting tumorigenicity and
malignancy in various cancer types. Here, we report that cisplatin treatment led to the …
malignancy in various cancer types. Here, we report that cisplatin treatment led to the …