Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction

NS Nurmohamed, JM Kraaijenhof, M Mayr… - European Heart …, 2023 - academic.oup.com
Given the limited accuracy of clinically used risk scores such as the Systematic COronary
Risk Evaluation 2 system and the Second Manifestations of ARTerial disease 2 risk scores …

Evaluation of large-scale proteomics for prediction of cardiovascular events

H Helgason, T Eiriksdottir, MO Ulfarsson, A Choudhary… - Jama, 2023 - jamanetwork.com
Importance Whether protein risk scores derived from a single plasma sample could be
useful for risk assessment for atherosclerotic cardiovascular disease (ASCVD), in …

[HTML][HTML] Atherosclerosis and its related laboratory biomarkers

V Della Corte, F Todaro, M Cataldi… - International Journal of …, 2023 - mdpi.com
Atherosclerosis constitutes a persistent inflammatory ailment, serving as the predominant
underlying condition for coronary artery disease (CAD), peripheral artery disease (PAD) …

Improved cardiovascular risk prediction using targeted plasma proteomics in primary prevention

RM Hoogeveen, JPB Pereira… - European Heart …, 2020 - academic.oup.com
Aims In the era of personalized medicine, it is of utmost importance to be able to identify
subjects at the highest cardiovascular (CV) risk. To date, single biomarkers have failed to …

[HTML][HTML] Advances in cardiovascular biomarker discovery

CM Ghantous, L Kamareddine, R Farhat, FA Zouein… - Biomedicines, 2020 - mdpi.com
Cardiovascular diseases are the leading causes of mortality worldwide. Among them,
hypertension and its pathological complications pose a major risk for the development of …

Early identification of cardiovascular risk using genomics and proteomics

IJ Kullo, LT Cooper - Nature Reviews Cardiology, 2010 - nature.com
Coronary heart disease (CHD) will soon become the leading cause of death and morbidity
in the world. Early detection and treatment of CHD is thus imperative to improve global …

[HTML][HTML] Circulating biomarkers for cardiovascular disease risk prediction in patients with cardiovascular disease

YK Wong, HF Tse - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Cardiovascular disease (CVD) is the leading cause of death globally. Risk assessment is
crucial for identifying at-risk individuals who require immediate attention as well as to guide …

Targeted proteomics improves cardiovascular risk prediction in secondary prevention

NS Nurmohamed, JP Belo Pereira… - European heart …, 2022 - academic.oup.com
Aims Current risk scores do not accurately identify patients at highest risk of recurrent
atherosclerotic cardiovascular disease (ASCVD) in need of more intensive therapeutic …

The molecular basis of predicting atherosclerotic cardiovascular disease risk

M Nayor, KJ Brown, RS Vasan - Circulation research, 2021 - Am Heart Assoc
Atherosclerotic cardiovascular disease (ASCVD) proceeds through a series of stages:
initiation, progression (or regression), and complications. By integrating known biology …

Protein biomarkers of new-onset cardiovascular disease: prospective study from the systems approach to biomarker research in cardiovascular disease initiative

X Yin, S Subramanian, SJ Hwang… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Incorporation of novel plasma protein biomarkers may improve current models
for prediction of atherosclerotic cardiovascular disease (ASCVD) risk. Approach and Results …