Application Value of Detection of High-Risk HPV Infection in Early Cervical Cancer Patients in Disease Diagnosis and Prognosis Evaluation.

Y Zhang, J Wang, R Zhang, F Lei, S Lai - Clinical Laboratory, 2020 - search.ebscohost.com
Background: To analyze the relationship between HPV infection and early cervical cancer
and postoperative survival outcomes. Methods: A total of 556 women were recruited to …

Evaluation of HPV E6/E7 mRNA Detection in Clinically Suspected Cases of Cervical Cancer with Abnormal Cytology: Time to Upgrade the Screening Protocols

B Sharma, V Lakhanpal, K Singh… - Journal of …, 2022 - thieme-connect.com
Background Human papillomavirus (HPV) E6/E7 mRNA tests determine the oncogenic
activity of the virus and represent a good clinical biomarker for predicting the risk of cervical …

The clinical value of HPV E6/E7 mRNA and HPV DNA in early screening of cervical cancer

J LI, P QU - Tianjin Medical Journal, 2016 - pesquisa.bvsalud.org
Objective To analyze the differences of positive detection rate and copy number of human
papillomavirus (HPV) DNA and E6/E7 mRNA between different grades of cervical lesions …

[HTML][HTML] Diagnostic performance of the E6/E7 mRNA-based Optimygene HR-HPV RT-qDx assay for cervical cancer screening

H Wang, H Kim, KH Park - International Journal of Infectious Diseases, 2019 - Elsevier
Objectives Pap smear and high-risk human papillomavirus (HR-HPV) DNA testing are the
most widely applied methods for cervical cancer screening, but both methods are limited by …

[PDF][PDF] Application of human papillomavirus in screening for cervical cancer and precancerous lesions

JL Wang, YZ Yang, WW Dong, J Sun, HT Tao… - Asian Pac J Cancer …, 2013 - academia.edu
Cervical cancer is a commonly-encountered malignant tumor in women. Cervical screening
is particularly important due to early symptoms being deficient in specificity. The main …

Clinical Value of Human Papillomavirus E6/E7 mRNA Detection in Screening for Cervical Cancer in Women Positive for Human Papillomavirus DNA or with Abnormal …

L Han, S Husaiyin, M Niyazi, F Zhao… - Clinical …, 2018 - search.ebscohost.com
Background: The detection of human papillomavirus (HPV) E6/E7 mRNA indicates a risk of
further deterioration in cervical lesions. We explored the clinical value of HPV E6/E7 mRNA …

Quantification of intracellular HPV E6/E7 mRNA expression increases the specificity and positive predictive value of cervical cancer screening compared to HPV DNA

G Coquillard, B Palao, BK Patterson - Gynecologic oncology, 2011 - Elsevier
OBJECTIVES: Current methods for HPV screening rely on the detection of L1 DNA from high
risk genotypes (HRHPV). These assays have very high negative predictive values (~ 99%) …

Diagnostic performance of HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR assays on formalin-fixed paraffin-embedded cervical tissue specimens from women with …

H Wang, G Kim, H Cho, S Kim, D Lee, S Park… - … and molecular pathology, 2015 - Elsevier
Human papillomavirus (HPV) is a major cause of cervical cancer, which is the third most
common cancer in women. Human telomerase reverse transcriptase (hTERT) and Ki67 are …

Molecular detection of human papillomavirus in women with minor-grade cervical cytology abnormalities

A Vince, M Ivanisevic, V Harni, D Skalko… - Journal of clinical …, 2001 - Elsevier
Background: Human papillomavirus (HPV) has been shown to be the major risk factor for the
development of cervical carcinoma, the second most common cancer among women …

[PDF][PDF] Comparative analysis of HPV DNA and LBC for screening of cervical cancer in women with unhealthy cervix

S Raj, M Srivastava - Age, 2022 - journal.barpetaogs.co.in
Background: The cervical cancer is one of the leading cause of cancer death among women
in developing and developed countries. Screening for cervical cancer is essential as the …