[HTML][HTML] Translating phage therapy into the clinic: recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

[HTML][HTML] Phage therapy in the 21st century: is there modern, clinical evidence of phage-mediated efficacy?

ST Abedon, KM Danis-Wlodarczyk, DR Alves - Pharmaceuticals, 2021 - mdpi.com
Many bacteriophages are obligate killers of bacteria. That this property could be medically
useful was first recognized over one hundred years ago, with 2021 being the 100-year …

Phage therapy in the twenty-first century: facing the decline of the antibiotic era; is it finally time for the age of the phage?

S Hesse, S Adhya - Annual review of microbiology, 2019 - annualreviews.org
Burgeoning problems of antimicrobial resistance dictate that new solutions be developed to
combat old foes. Use of lytic bacteriophages (phages) for the treatment of drug-resistant …

Phage therapy in clinical practice: treatment of human infections

E Kutter, D De Vos, G Gvasalia… - Current …, 2010 - ingentaconnect.com
Phage therapy is the application of bacteria-specific viruses with the goal of reducing or
eliminating pathogenic or nuisance bacteria. While phage therapy has become a broadly …

[HTML][HTML] Phage therapy: a renewed approach to combat antibiotic-resistant bacteria

KE Kortright, BK Chan, JL Koff, PE Turner - Cell host & microbe, 2019 - cell.com
Phage therapy, long overshadowed by chemical antibiotics, is garnering renewed interest in
Western medicine. This stems from the rise in frequency of multi-drug-resistant bacterial …

Phage therapy

JN Housby, NH Mann - Drug discovery today, 2009 - Elsevier
There is a renaissance of interest in the antimicrobial potential of phages as more
pathogens become multiply antibiotic resistant. Phage therapy is not a new concept, and it is …

Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

[HTML][HTML] Phage therapy: what have we learned?

A Górski, R Międzybrodzki, M Łobocka… - Viruses, 2018 - mdpi.com
In this article we explain how current events in the field of phage therapy may positively
influence its future development. We discuss the shift in position of the authorities …

Phage therapy: Current status and perspectives

A Górski, R Międzybrodzki, G Węgrzyn… - Medicinal research …, 2020 - Wiley Online Library
The spread of antimicrobial resistant bacterial pathogens combined with the lack of new
drug classes in the antibiotic pipeline causes a resurgence of the use of bacterial viruses …

What are the limitations on the wider therapeutic use of phage?

A Henein - Bacteriophage, 2013 - Taylor & Francis
Bacterial resistance to antibiotics poses a serious health threat. Since research into new
antibiotics is not progressing at the same rate as the development of bacterial resistance …