New tests to detect antiphospholipid antibodies: antiprothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies

S Sciascia, MA Khamashta, ML Bertolaccini - Current rheumatology reports, 2014 - Springer
Antiprothrombin antibodies have been proposed as potential new biomarkers for thrombosis
and/or pregnancy morbidity in the setting of the antiphospholipid syndrome (APS) …

Clinical relevance of antiprothrombin antibodies

T Atsumi, T Koike - Autoimmunity Reviews, 2002 - Elsevier
Antiprotrombin antibodies belong to the family of antiphospholipid antibodies (aPLs). The
clinical relevance of antiprothrombin antibodies has not been established and it depends on …

Detection of antiphosphatidylserine/prothrombin antibodies and their potential diagnostic value

P Žigon, S Čučnik, A Ambrožič, T Kveder… - Journal of …, 2013 - Wiley Online Library
Antiprothrombin antibodies, measured with phosphatidylserine/prothrombin complex
(aPS/PT) ELISA, have been reported to be associated with antiphospholipid syndrome …

Antiphosphatidylserine/prothrombin antibodies (aPS/PT) as potential markers of antiphospholipid syndrome

A Vlagea, A Gil, MV Cuesta, F Arribas… - Clinical and Applied …, 2013 - journals.sagepub.com
The antiphospholipid antibodies present in antiphospholipid syndrome (APS) are directed at
a number of phospholipid-binding proteins: β2 glycoprotein I (β2GPI), prothrombin, and so …

Antiprothrombin antibodies—are they worth assaying?

T Atsumi, O Amengual, S Yasuda, T Koike - Thrombosis research, 2004 - Elsevier
According to the preliminary classification criteria of the antiphospholipid syndrome
(APS)(Sapporo Criteria), β2-glycoprotein I (β2GPI)-dependent anticardiolipin antibodies …

Anti‐prothrombin antibodies: assay conditions and clinical associations in the anti‐phospholipid syndrome

S Donohoe, IJ Mackie, D Isenberg… - British journal of …, 2001 - Wiley Online Library
Anti‐phospholipid antibodies (aPL) are associated with an increased risk of thrombosis and
recurrent fetal loss. Antibodies to prothrombin (aPT) have been associated with the anti …

Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome

S Sciascia, G Sanna, V Murru… - Thrombosis and …, 2014 - thieme-connect.com
Antibodies to prothrombin are detected by directly coating prothrombin on irradiated ELISA
plates (aPT) or by using the phosphatidylserine/prothrombin complex as antigen (aPS/PT) …

An overview of laboratory testing for antiphospholipid antibodies

EJ Favaloro, L Pasalic - Hemostasis and Thrombosis: Methods and …, 2023 - Springer
Antiphospholipid antibodies (aPL) represent a group of autoantibodies directed against
phospholipids. These antibodies may arise in a number of autoimmune conditions, of which …

Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations

A Tincani, C Casu, S Cartella, T Ziglioli, R Cattaneo - Reumatismo, 2010 - reumatismo.org
Antiphospholipid antibodies (aPL) represent a heterogeneous group of antibodies that
recognize various antigenic targets including beta2 glycoprotein I (β2GPI), prothrombin (PT) …

Anti-phosphatidylserine/prothrombin antibodies: an additional diagnostic marker for APS?

F Pregnolato, CB Chighizola, S Encabo, Z Shums… - Immunologic …, 2013 - Springer
Among the diagnostic assays for anti-phospholipid syndrome (APS), lupus anticoagulant
(LA) is the strongest predictor of thrombosis; however, it presents several limitations as …