Treatment of childhood acute lymphoblastic leukemia: prognostic factors and clinical advances

LM Vrooman, LB Silverman - Current hematologic malignancy reports, 2016 - Springer
While the majority of children and adolescents with newly diagnosed childhood acute
lymphoblastic leukemia (ALL) will be cured, as many as 20% of patients will experience …

Newly diagnosed childhood acute lymphoblastic leukemia: update on prognostic factors and treatment

LB Silverman, SE Sallan - Current opinion in hematology, 2003 - journals.lww.com
The development of effective therapy for children with acute lymphoblastic leukemia is one
of the great successes of clinical hematology andoncology. Fifty years ago, childhood acute …

Treatment of childhood acute lymphoblastic leukemia

M Stanulla, M Schrappe - Seminars in hematology, 2009 - Elsevier
Childhood acute lymphoblastic leukemia (ALL) is the most common malignancy of
childhood. Studies in ALL have been a model for clinical and basic research beyond …

Novel therapy for childhood acute lymphoblastic leukemia

R Santiago, S Vairy, D Sinnett… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: During recent decades, the prognosis of childhood acute lymphoblastic
leukemia (ALL) has improved dramatically, nowadays, reaching a cure rate of almost 90 …

Acute lymphoblastic leukemia

WL Carroll, T Bhatla - Lanzkowsky's manual of pediatric hematology and …, 2016 - Elsevier
Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood with a
peak incidence between 2 and 6 years of age. Recent advances in understanding the …

Acute lymphoblastic leukemia in children. Advances and prospectus

W Archie Bleyer - Cancer, 1990 - Wiley Online Library
During the past decade, advances in the treatment of childhood acute lymphoblastic
leukemia (ALL) have continued, largely due to improved disease‐free survival of poor …

Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

CH Pui, CG Mullighan, WE Evans… - Blood, The Journal of …, 2012 - ashpublications.org
Improved supportive care, more precise risk stratification, and personalized chemotherapy
based on the characteristics of leukemic cells and hosts (eg, pharmacokinetics and …

A revised definition for cure of childhood acute lymphoblastic leukemia

CH Pui, D Pei, D Campana, C Cheng, JT Sandlund… - Leukemia, 2014 - nature.com
With improved contemporary therapy, we reassess long-term outcome in patients
completing treatment for childhood acute lymphoblastic leukemia (ALL) to determine when …

The treatment of adolescents and young adults with acute lymphoblastic leukemia

DJ DeAngelo - ASH Education Program Book, 2005 - ashpublications.org
Intensive chemotherapy regimens for children with acute lymphoblastic leukemia (ALL) have
greatly improved, and the majority of children with precursor B-cell ALL are able to achieve a …

Pediatric acute lymphoblastic leukemia: challenges and controversies in 2000

CA Felix, BJ Lange… - ASH Education Program …, 2000 - ashpublications.org
This article discusses ways in which pediatric patients with acute lymphoblastic leukemia
(ALL) can be stratified to receive intensive and less intensive therapies in order to decrease …