Sepsis is the overwhelming inflammatory response to infection, especially bacterial infection
and associated bacterial products. It has major healthcare impacts, affecting an estimated 19 …

Despite extensive investigations, an effective treatment for sepsis remains elusive and a
better understanding of the inflammatory response to infection is required to identify …

Despite extensive investigations, an effective treatment for sepsis remains elusive and a
better understanding of the inflammatory response to infection is required to identify …

Lysophosphatidylcholine Acyltransferases (LPCATs) are Lipid modifying enzymes that
significantly regulate changes in the glycerophospholipid components of the macrophage …

Lysophospholipid acyltransferases (LPLATs) regulate the diversification of fatty acid
composition in biological membranes. Lysophosphatidylcholine acyltransferases (LPCATs) …

Molecular and biochemical analyses of membrane phospholipids have revealed that, in
addition to their physico-chemical properties, the metabolites of phospholipids play a crucial …

Mammalian cell membrane phosphatidylcholines (PCs), the major phospholipids, exhibit
diversity which is controlled by Lands' cycle or PC remodeling pathway …

Sepsis, an overwhelming inflammatory response to infection, is a major cause of morbidity
and mortality worldwide and has no specific therapy. Phospholipid metabolites, such as …

LPCAT3, a subtype of lysophosphatidylcholine acyltransferases, is a key enzyme in
phosphatidylcholine remodeling pathway and plays a significant role in mediating …

Macrophages are key antigen presenting cells that also secrete cytokines during
inflammation. They can be polarised to M1 or M2 phenotypes. Molecules such as CD206 …