The Hippo pathway and its downstream effectors, the transcriptional co-activators Yes-
associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) …

The Hippo signaling pathway is a highly-conserved developmental pathway that plays an
essential role in organ size control, tumor suppression, tissue regeneration and stem cell …

The Hippo signalling pathway is an emerging growth control and tumour suppressor
pathway that regulates cell proliferation and stem cell functions. Defects in Hippo signalling …

The Hippo pathway is an evolutionarily conserved signalling pathway with key roles in
organ development, epithelial homeostasis, tissue regeneration, wound healing and …

While several organs in mammals retain partial regenerative capability following tissue
damage, the underlying mechanisms remain unclear. Recently, the Hippo signaling …

Hippo signaling was first identified in Drosophila as a key controller of organ size by
regulating cell proliferation and anti-apoptosis. Subsequent studies have shown that this …

YAP (Yes-associated protein) and TAZ (transcriptional coactivator with PDZ-binding motif)
are major downstream effectors of the Hippo pathway that influences tissue homeostasis …

Complex physiological processes control whether stem cells self-renew, differentiate or
remain quiescent. Two decades of research have placed the Hippo pathway, a highly …

The Hippo pathway was originally identified and named through screening for mutations in
Drosophila, and the core components of the Hippo pathway are highly conserved in …

The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional
co-activator proteins that play key roles in many diverse biological processes, ranging from …