Serrated adenomas (SA) of the colorectum show features intermediate between hyperplastic
polyps (HP) and adenomas. HP and SA are related lesions and there is now strong …

The fundamental view that colon adenocarcinomas arise only from conventional adenomas
has been challenged by the now recognized hyperplastic polyp-serrated adenoma …

The serrated polyp pathway is a histopathological sequence that begins in a hyperplastic
polyp, or precursor serrated aberrant crypt focus, and has the potential to end in a colonic …

Serrated polyps have long been thought to lack malignant potential in the human
colorectum. However, identification of the serrated pathway to colorectal cancer based on …

Serrated polyps of the large intestine comprise a heterogeneous group of mucosal lesions
that includes nondysplastic polyps, such as hyperplastic polyps and sessile serrated polyps …

Approximately 30% of colorectal carcinomas develop via the serrated neoplasia pathway
characterized by widespread DNA methylation and frequent BRAF mutation. Serrated …

In the past two decades, besides conventional adenoma pathway, a subset of colonic
lesions, including hyperplastic polyps, sessile serrated adenoma/polyps, and traditional …

In recent years, an alternative pathway of colorectal cancer development has been
described in which serrated polyps replace the traditional adenoma as the precursor lesion …

Until recently, two major types of colorectal epithelial polyps were distinguished: the
adenoma and the hyperplastic polyp. While adenomas—because of their cytological atypia …

Serrated adenocarcinoma is a recently described subset of colorectal cancer (CRC), which
account for about 10% of all CRCs and follows an alternative pathway in which serrated …