The discovery of direct cell reprogramming and induced pluripotent stem (iPS) cell
technology opened up new avenues for the application of non-viral, transposon-based gene …

Induced pluripotent stem (iPS) cell technology involves reprogramming somatic cells to a
pluripotent state. The original technology used to produce these cells requires viral gene …

The generation of induced pluripotent stem (iPS) cells represents a promising approach for
innovative cell therapies. The original method requires viral transduction of several …

Transposon gene delivery systems offer an alternative, non-viral-based approach to
generate induced pluripotent stem cells (iPSCs). Here we used the Sleeping Beauty (SB) …

Transposon technology is a particularly attractive non-viral gene delivery paradigm that
allows for efficient genomic integration into a variety of different cell types. In particular …

Induced pluripotent stem cells (iPSCs) have revolutionized the stem cell field. iPSCs are
most often produced by using retroviruses. However, the resulting cells may be ill-suited for …

Induced pluripotent stem cells (iPSCs) have been generated from somatic cells by
transgenic expression of Oct4 (Pou5f1), Sox2, Klf4 and Myc. A major difficulty in the …

Adult stem cells and induced pluripotent stem cells (iPS) hold great promise for regenerative
medicine. The development of robust nonviral approaches for stem cell gene transfer would …

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) allows the
derivation of personalized stem cells. Transposon transgenesis is a novel and viable …

The generation of patient‐specific induced pluripotent stem (iPS) cells provides an
invaluable resource for cell therapy, in vitro modeling of human disease, and drug …