Caveolae, DIGs, and the dynamics of sphingolipid—cholesterol microdomains

T Harder, K Simons - Current opinion in cell biology, 1997 - Elsevier
There is accumulating evidence that lateral assemblies (rafts) of sphingolipids and
cholesterol form platforms that serve to support numerous cellular events in membrane traffic …

[HTML][HTML] Relationship between cholesterol trafficking and signaling in rafts and caveolae

CJ Fielding, PE Fielding - Biochimica et Biophysica Acta (BBA) …, 2003 - Elsevier
Caveolae and lipid rafts are two distinct populations of free cholesterol, sphingolipid
(FC/SPH)-rich cell surface microdomains. They differ in stability, shape, and the presence or …

Membrane microdomains and caveolae

TV Kurzchalia, RG Partan - Current opinion in cell biology, 1999 - Elsevier
Glycosphingolipid-and cholesterol-enriched microdomains, or rafts, within the plasma
membrane of eukaryotic cells have been implicated in many important cellular processes …

Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae

NM Hooper - Molecular membrane biology, 1999 - Taylor & Francis
Within the cell membrane glycosphingolipids and cholesterol cluster together in distinct
domains or lipid rafts, along with glycosyl-phosphatidylinositol (GPI)-anchored proteins in …

Lipid rafts, caveolae, and their endocytosis

P Lajoie, IR Nabi - International review of cell and molecular biology, 2010 - Elsevier
Lipid rafts are plasma membrane microdomains enriched in cholesterol and sphingolipids
that are involved in the lateral compartmentalization of molecules at the cell surface …

[HTML][HTML] Role of cholesterol in lipid raft formation: lessons from lipid model systems

JR Silvius - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2003 - Elsevier
Biochemical and cell-biological experiments have identified cholesterol as an important
component of lipid 'rafts' and related structures (eg, caveolae) in mammalian cell …

Caveolae/raft-dependent endocytosis

IR Nabi, PU Le - The Journal of cell biology, 2003 - rupress.org
Although caveolae are well-characterized subdomains of glycolipid rafts, their distinctive
morphology and association with caveolins has led to their internalization being considered …

Caveolin, cholesterol, and lipid bodies

S Martin, RG Parton - Seminars in cell & developmental biology, 2005 - Elsevier
In mammalian cells a complex interplay regulates the distribution of cholesterol between
intracellular membrane compartments. One important aspect of cholesterol regulation is …

Integrin-mediated adhesion regulates membrane order

K Gaus, S Le Lay, N Balasubramanian… - The Journal of cell …, 2006 - rupress.org
The properties of cholesterol-dependent domains (lipid rafts) in cell membranes have been
controversial. Because integrin-mediated cell adhesion and caveolin both regulate …

Structure and function of sphingolipid-and cholesterol-rich membrane rafts

DA Brown, E London - Journal of Biological Chemistry, 2000 - ASBMB
It is well known that separate domains with different lipid compositions can exist in
liposomes containing mixtures of different phospholipids. The question of whether cellular …