[HTML][HTML] Lymphodepletion–an essential but undervalued part of the chimeric antigen receptor T-cell therapy cycle

B Lickefett, L Chu, V Ortiz-Maldonado… - Frontiers in …, 2023 - frontiersin.org
Lymphodepletion (LD) or conditioning is an essential step in the application of currently
used autologous and allogeneic chimeric antigen receptor T-cell (CAR-T) therapies as it …

The shifting roles and toxicities of cellular therapies in B‐cell malignancies

OL Makos, CR D'Angelo - Transplant Infectious Disease, 2023 - Wiley Online Library
Cellular therapies provide a curative‐intent option for patients with relapsedand refractory
lymphomas. Current options including high dose chemotherapyfollowed by autologous or …

[HTML][HTML] Cellular therapy updates in B-cell lymphoma: the state of the CAR-T

ZD Crees, A Ghobadi - Cancers, 2021 - mdpi.com
Simple Summary B-cell lymphomas are the most commonly occurring blood cancer and the
second leading cause of cancer-related death among blood cancers. Chemotherapy and …

Cellular therapy in lymphoma

A Sureda, PJ Lugtenburg, MJ Kersten… - Hematological …, 2023 - Wiley Online Library
CD19‐directed chimeric antigen receptor (CAR) T‐cell therapy has had a dramatic impact
on the natural history and survival of patients with high‐risk B‐cell non‐Hodgkin lymphoma …

Emerging role of autologous CD19 CAR T-cell therapies in the second-line setting for large B-cell lymphoma: A game changer?

R Mohty, MA Moustafa, M Aljurf, H Murthy… - … /Oncology and Stem Cell …, 2022 - hosct.org
Chimeric antigen receptor T-cell (CAR T) therapy has been proven effective in the third-line
(and beyond) setting in patients with large B-cell lymphoma (LBCL). Until recently, high …

[HTML][HTML] Efficiency and safety of autologous chimeric antigen receptor T-cells therapy used for patients with lymphoma: A systematic review and meta-analysis

G Cao, L Lei, X Zhu - Medicine, 2019 - journals.lww.com
Background: Chimeric antigen receptor (CAR) T-cell therapy has produced promising
response rates in patients with B cell malignancies. However, previous meta-analyses have …

CAR T-cell therapy for B-cell lymphomas: clinical trial results of available products

JC Chavez, C Bachmeier… - Therapeutic …, 2019 - journals.sagepub.com
Adoptive cellular immunotherapy with chimeric antigen receptor (CAR) T cell has changed
the treatment landscape of B-cell non-Hodgkin's lymphoma (NHL), especially for aggressive …

[HTML][HTML] Chimeric Antigen Receptor-T Cell Therapy for Lymphoma: New Settings and Future Directions

CB Savelli, M Clerico, B Botto, C Secreto, F Cavallo… - Cancers, 2024 - ncbi.nlm.nih.gov
In the last decade, anti-CD19 CAR-T cell therapy has led to a treatment paradigm shift for B-
cell non-Hodgkin lymphomas, first with the approval for relapsed/refractory (R/R) large B-cell …

Chimeric antigen receptor modified T cell therapy in B cell non‐Hodgkin lymphomas

A Levin, NN Shah - American Journal of Hematology, 2019 - Wiley Online Library
Chimeric antigen receptor modified T (CAR‐T) cell therapy against the CD19 antigen has
revolutionized the therapeutic landscape for patients with relapsed, refractory B cell non …

Potentials, challenges and future of chimeric antigen receptor T-cell therapy in non-Hodgkin lymphomas

TC El-Galaly, CY Cheah, D Kristensen… - Acta …, 2020 - Taylor & Francis
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma
subtype. Disease progression or relapse following frontline chemoimmunotherapy, largely in …