[HTML][HTML] Therapeutic potential and limitations of curcumin as antimetastatic agent

P Dytrych, Z Kejík, J Hajduch, R Kaplánek… - Biomedicine & …, 2023 - Elsevier
Abstract Treatment of metastatic cancer is one of the biggest challenges in anticancer
therapy. Curcumin is interesting nature polyphenolic compound with unique biological and …

[HTML][HTML] Farmer to pharmacist: curcumin as an anti-invasive and antimetastatic agent for the treatment of cancer

D Bandyopadhyay - Frontiers in chemistry, 2014 - frontiersin.org
A huge number of compounds are widely distributed in nature and many of these possess
medicinal/biological/pharmacological activity. Curcumin, a polyphenol derived from the …

[HTML][HTML] The role of curcumin in prevention and management of metastatic disease

BE Bachmeier, PH Killian, D Melchart - International journal of molecular …, 2018 - mdpi.com
In the last two decades, targeted therapies have enhanced tumor patient care and treatment
success, however, metastatic growth still cannot be stopped efficiently and, therefore …

Molecular mechanisms of anti-metastatic activity of curcumin

YI Deng, E Verron, R Rohanizadeh - Anticancer Research, 2016 - ar.iiarjournals.org
Cancer is the leading cause of death worldwide. Although cancer occurs as a localized
disease, its morbidity and mortality rates remain high due to the ability of cancer cells to …

[HTML][HTML] The synergistic effects of curcumin and chemotherapeutic drugs in inhibiting metastatic, invasive and proliferative pathways

M Younes, R Mardirossian, L Rizk, T Fazlian… - Plants, 2022 - mdpi.com
Curcumin, the main phytochemical identified from the Curcuma longa L. family, is one of the
spices used in alternative medicine worldwide. It has exhibited a broad range of …

Curcumin and its formulations: potential anti-cancer agents

JL Ji, XF Huang, HL Zhu - Anti-Cancer Agents in Medicinal …, 2012 - ingentaconnect.com
Curcumin, one of the most studied chemopreventive agents, is a natural compound
extracted from Curcuma longa L. Extensive research over the last half century has revealed …

[HTML][HTML] Antitumoral activities of curcumin and recent advances to improve its oral bioavailability

MC Nocito, A De Luca, F Prestia, P Avena, D La Padula… - Biomedicines, 2021 - mdpi.com
Curcumin, a main bioactive component of the Curcuma longa L. rhizome, is a phenolic
compound that exerts a wide range of beneficial effects, acting as an antimicrobial …

[HTML][HTML] A review of curcumin and its derivatives as anticancer agents

MA Tomeh, R Hadianamrei, X Zhao - International journal of molecular …, 2019 - mdpi.com
Cancer is the second leading cause of death in the world and one of the major public health
problems. Despite the great advances in cancer therapy, the incidence and mortality rates of …

[PDF][PDF] Curcumin: the multi-targeted therapy for cancer regression

DMS Hossain, S Bhattacharyya, T Das… - Frontiers in Bioscience …, 2012 - academia.edu
Introduction 3. Introductory background of curcumin 3.1. Physical and chemical backdrop
3.2. Safety and toxicity 3.3. Biotransformation and bioavailability 3.4. On the way of …

Anticancer activity of curcumin and its analogues: preclinical and clinical studies

A Allegra, V Innao, S Russo, D Gerace… - Cancer …, 2017 - Taylor & Francis
Curcumin has been shown to have a wide variety of therapeutic effects, ranging from anti-
inflammatory, chemopreventive, anti-proliferative, and anti-metastatic. This review provides …