The comparison of effectiveness of various potential predictors of response to treatment with SSRIs in patients with depressive disorder

M Bares, T Novak, M Brunovsky… - The Journal of …, 2017 - journals.lww.com
The substantial non-response rate in depressive patients indicates a continuing need to
identify predictors of treatment outcome. The aim of this 6-week, open-label study was (1) to …

The antidepressant treatment response index as a predictor of reboxetine treatment outcome in major depressive disorder

MM Caudill, AM Hunter, IA Cook… - Clinical EEG and …, 2015 - journals.sagepub.com
Biomarkers to predict clinical outcomes early during the treatment of major depressive
disorder (MDD) could reduce suffering and improve outcomes. A quantitative …

Early predictors of two month response with mianserin and selective serotonin reuptake inhibitors and influence of definition of outcome on prediction

I Berlin, F Lavergne - European psychiatry, 1998 - Elsevier
In order to identify clinical and demographic variables that predict response to
antidepressants and to analyse prediction of outcome as a function of definition of outcome …

Prediction of short-term antidepressant response using probabilistic graphical models with replication across multiple drugs and treatment settings

AP Athreya, T Brückl, EB Binder, A John Rush… - …, 2021 - nature.com
Heterogeneity in the clinical presentation of major depressive disorder and response to
antidepressants limits clinicians' ability to accurately predict a specific patient's eventual …

Two items on the Hamilton Depression rating scale are effective predictors of remission: comparison of selective serotonin reuptake inhibitors with the combined …

PH Silverstone, R Entsuah… - International clinical …, 2002 - journals.lww.com
Recent studies have shown that the use of subscales derived from the Hamilton Depression
(HAM-D) rating scale are just as reliable and enhance sensitivity for detecting response and …

The early improvement of depressive symptoms as a potential predictor of response to antidepressants in depressive patients who failed to respond to previous …

M Bares, T Novak, M Kopecek, P Stopkova, J Kozeny… - European …, 2012 - Elsevier
INTRODUCTION: Current studies suggest that improvement of depressive symptoms after 2
weeks of treatment could predict the subsequent response. The aim of our study was to …

Evidence that the SSRI dose response in treating major depression should be reassessed: a meta‐analysis

CB Baker, R Tweedie, S Duval… - Depression and …, 2003 - Wiley Online Library
The limitations in design and analysis of currently available dose‐response studies of SSRI
treatment of major depression have led to the conclusion that dose response is flat. We …

The antidepressant treatment response index and treatment outcomes in a placebo-controlled trial of fluoxetine

AM Hunter, IA Cook, SD Greenwald… - Journal of Clinical …, 2011 - journals.lww.com
Recent research aims at developing a biomarker to predict antidepressant treatment
outcomes in major depressive disorder. The Antidepressant Treatment Response (ATR) …

Antidepressant response in major depressive disorder: a meta-regression comparison of randomized controlled trials and observational studies

F Naudet, AS Maria, B Falissard - PLoS One, 2011 - journals.plos.org
Background To compare response to antidepressants between randomized controlled trials
(RCTs) and observational trials. Methods and Findings Published and unpublished studies …

Prospective testing of a neurophysiologic biomarker for treatment decisions in major depressive disorder: the PRISE-MD trial

IA Cook, AM Hunter, MM Caudill, MJ Abrams… - Journal of psychiatric …, 2020 - Elsevier
Abstract Management of Major Depressive Disorder (MDD) might be improved by a
biomarker to predict whether a selected medication is likely to lead to remission. We …