Objective: When prescribed with opioids, sedative-hypnotics substantially increase the risk
of overdose. The objective of this paper was to describe characteristics and trends in opioid …

Objective To evaluate co-prescribing of sedatives hypnotics and opioids. Design
Retrospective study evaluating the association of patient characteristics and comorbidities …

Objective Describe trends in opioid plus high-risk medication coprescribing in the USA.
Design Analyses of serial, cross-sectional, nationally representative data of the National …

Background: The Centers for Disease Control and Prevention recognizes Medicaid as a
high-risk population for fatal opioid overdose. Further research is needed to identify factors …

Co-prescribing of opioids and benzodiazepines can lead to overdoses and mortality. This
retrospective study analyzed prescription claims data collected in 2016. A national …

Objective Due to increased risks of overdose fatalities and injuries associated with
coprescription of opioids and benzodiazepines, healthcare systems have prioritized …

Objective (s) This study aimed to characterize the co-utilization of non-benzodiazepine
sedative 'Z'-drugs with opioids at ambulatory care visits in the United States. Design A cross …

Background Concurrent use of sedatives, especially anxiolytics, and opioids is associated
with increased risk of medication-related harms. To the extent that multiple prescribers are …

Background Concurrent use of benzodiazepines in opioid users has been linked to a higher
risk of an emergency room visit or inpatient admission for opioid overdose and death from …

Background: Co-prescribing opioids and benzodiazepines increases overdose risk. A
paucity of literature exists evaluating strategies to improve safety of co-prescribing. This …