Regulatory mechanisms of microRNA expression

LF Gulyaeva, NE Kushlinskiy - Journal of translational medicine, 2016 - Springer
MicroRNAs (miRs, miRNAs) are small molecules of 18–22 nucleotides that serve as
important regulators of gene expression at the post-transcriptional level. One of the …

Transcriptional and epigenetic regulation of human microRNAs

Z Wang, H Yao, S Lin, X Zhu, Z Shen, G Lu, WS Poon… - Cancer letters, 2013 - Elsevier
MicroRNAs (miRNAs) are members of non-coding RNAs. They are involved in diverse
biological functions. MiRNAs are precisely regulated in a tissue-and developmental-specific …

MicroRNA (miRNA) in cancer

KB Reddy - Cancer cell international, 2015 - Springer
In recent years, there has been a tremendous and growing interest among researchers to
investigate the role of mircoRNA (miRNA) in normal cellular as well as in disease processes …

[HTML][HTML] MicroRNA: A signature for cancer progression

BM Hussen, HJ Hidayat, A Salihi, DK Sabir… - Biomedicine & …, 2021 - Elsevier
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

MicroRNAs: a puzzling tool in cancer diagnostics and therapy

B D'ANGELO, E Benedetti, A Cimini… - Anticancer …, 2016 - ar.iiarjournals.org
MicroRNAs (miRNAs) constitute a dominating class of small RNAs that regulate diverse
cellular functions. Due the pivotal role of miRNAs in biological processes, a deregulated …

MicroRNAs: novel regulators in the hallmarks of human cancer

K Ruan, X Fang, G Ouyang - Cancer letters, 2009 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs of 18–25 nucleotides in length that
function as negative regulators. miRNAs post-transcriptionally regulate gene expression by …

[PDF][PDF] MicroRNA biogenesis, functionality and cancer relevance

B Kusenda, M Mraz, J Mayer… - Biomed Pap Med Fac …, 2006 - researchgate.net
Background: MicroRNAs (miRNA) are small non–coding RNAs that negatively regulate
gene expression in a sequence–specific manner. Post–transcriptional silencing of target …

The role of MicroRNAs in human cancer

Y Peng, CM Croce - Signal transduction and targeted therapy, 2016 - nature.com
MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

MicroRNA epigenetic alterations in human cancer: one step forward in diagnosis and treatment

N Yang, G Coukos, L Zhang - International journal of cancer, 2008 - Wiley Online Library
MicroRNAs (miRNAs) are approximately 22 nt non‐coding RNAs, which regulate gene
expression in a sequence‐specific manner via translational inhibition or messenger RNA …

[HTML][HTML] MicroRNAs: molecular features and role in cancer

E Lages, H Ipas, A Guttin, H Nesr, F Berger… - Frontiers in …, 2012 - ncbi.nlm.nih.gov
Abstract microRNAs (miRNAs) are small noncoding endogenously produced RNAs that play
key roles in controlling the expression of many cellular proteins. Once they are recruited and …