R-Aminophosphonic acids are broadly defined as analogues of amino acids in which the
carboxylic group is replaced by a phosphonic acid or related group (usually phosphonous or …

Aminophosphonic acids are an important group of medicinal compounds, and their
synthesis has been a focus of considerable attention in synthetic organic chemistry as well …

As phosphorus analogs of natural α‐amino acids, α‐aminophosphonic acids and their
derivatives have attracted wide attention in chemistry, medicine, and agricultural science. In …

Organophosphorus compounds are important substrates in the study of biochemical
processes, 1 and compounds of tetracoordinate pentavalent phosphorus are widely used as …

1. Introduction a-Aminophosphonic acids and their derivatives exhibit diverse biological
activities that are the basis of their important pharmacological applications. 1 Their …

In recent years, phosphonic acids and their derivatives have received increasing attention
as analogues of a series of naturally occurring phosphates and as “bio-isosteric phosphorus …

This review presents a comprehensive account of methods which are commonly applied for
the synthesis of α-aminophosphonic acids. In the following order, protocols based on the …

The biological activity and natural occurrence of the aminophosphonic acids were described
half a century ago. Since then the chemistry and biology of this class of compounds have …

Diaryl esters of α-aminophosphonates are a group of low molecular weight inhibitors of
serine proteases. For over 30 years these molecules have captured the attention of …

1. Introduction a-Aminoalkylphosphonic acids 1 are structurally analogous to a-amino acids
2, obtained by isosteric substitution of the planar and less bulky carboxylic acid (CO2H) by a …