The Association between vascular abnormalities and glaucoma—What comes first?

X Wang, M Wang, H Liu, K Mercieca, J Prinz… - International Journal of …, 2023 - mdpi.com
Glaucoma is a leading cause of irreversible blindness worldwide. While intraocular pressure
(IOP) presents a major risk factor, the underlying pathophysiology still remains largely …

Vascular aspects in glaucoma: from pathogenesis to therapeutic approaches

AS Mursch-Edlmayr, M Bolz, C Strohmaier - International Journal of …, 2021 - mdpi.com
Glaucomatous optic neuropathies have been regarded as diseases caused by high
intraocular pressure for a long time, despite the concept of vascular glaucoma dating back to …

[HTML][HTML] Controversies in the vascular theory of glaucomatous optic nerve degeneration

SS Ahmad - Taiwan journal of ophthalmology, 2016 - Elsevier
An understanding of the pathogenesis of glaucoma is one of the foundations in glaucoma
management. A number of theories have been presented to explain glaucomatous neural …

Advances in understanding glaucoma pathogenesis: a multifaceted molecular approach for clinician scientists

E Ekici, S Moghimi - Molecular Aspects of Medicine, 2023 - Elsevier
Glaucoma, a leading cause of irreversible blindness worldwide, is a spectrum of
neurodegenerative diseases characterized by the gradual deterioration of retinal ganglion …

Vascular dysregulation in glaucoma: retinal vasoconstriction and normal neurovascular coupling in altitudinal visual field defects

W Zhou, BA Sabel - EPMA Journal, 2023 - Springer
Purpose Vision loss in glaucoma is not only associated with elevated intraocular pressure
and neurodegeneration, but vascular dysregulation (VD) is a major factor. To optimize …

Association between vascular comorbidity and glaucoma progression: A four-year observational study

AM Dascalu, D Stana, VA Nicolae… - Experimental and …, 2021 - spandidos-publications.com
Glaucoma, one of the significant causes of blindness worldwide, is a chronic optic
neuropathy, characterized by progressive loss of retinal ganglion cells and specific …

Endothelial dysfunction in glaucoma

H Resch, G Garhofer, G Fuchsjäger‐Mayrl… - Acta …, 2009 - Wiley Online Library
Glaucoma is a group of ocular diseases characterized by optic neuropathy associated with
loss of the retinal nerve fibre layer and re‐modelling of the optic nerve head, and a …

Vascular risk factors in glaucoma: a review

M Yanagi, R Kawasaki, JJ Wang… - Clinical & …, 2011 - Wiley Online Library
Glaucoma, one of the major causes of blindness in the world, is a progressive optic
neuropathy. Elevated intraocular pressure is a well‐known major risk factor for glaucoma. In …

Clinical clues of vascular dysregulation and its association with glaucoma

MT Nicolela - Canadian Journal of Ophthalmology, 2008 - Elsevier
Vascular dysregulation is a condition in which blood flow is not properly distributed to meet
the demands of different tissues and could lead to overperfusion or underperfusion …

The neurovascular unit in glaucomatous neurodegeneration

LK Wareham, DJ Calkins - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Glaucoma is a neurodegenerative disease of the visual system and leading cause of
blindness worldwide. The disease is associated with sensitivity to intraocular pressure (IOP) …