The concept of 'idiopathic'Parkinson's disease (PD) as a single entity has been challenged
with the identification of several clinical subtypes, pathogenic genes and putative causative …

Objective: Parkinson's disease (PD) is a progressive neurological disorder characterised by
a large number of motor and non-motor features that can impact on function to a variable …

Emerging concepts suggest that a multitude of pathology ranging from misfolding of alpha-
synuclein to neuroinflammation, mitochondrial dysfunction, and neurotransmitter driven …

After Alzheimer's disease, Parkinson's disease (PD) is the second most prevalent and
incidental neurodegenerative disorder, affecting more than 2% of the population older than …

Psychotic symptoms in Parkinson's disease (PD) are relatively common and, in addition to
creating a disturbance in patients' daily lives, have consistently been shown to be …

Considerable advances made in defining the aetiology, pathogenesis, and pathology of
Parkinson's disease (PD) have resulted in the development and rapid expansion of the …

Parkinson's disease is an increasingly common neurodegenerative condition, which causes
not only dysfunction of movement but also a broad range of nonmotor features, including …

Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars
compacta and subsequent reduction of dopamine levels in striatum are associated with …

It took almost 100 years before a meaningful advance occurred in any basic science
understanding of Parkinson disease (PD) following James Parkinson's description in 1817 …

Context: Parkinson's disease (PD) is the second common progressive neurodegenerative
disease, distressing older men and is prevalent Worldwide. Objectives: This article is aimed …