Parkinsonism is a clinical syndrome, which is characterized by bradykinesia, rigidity, rest
tremor, and postural instability. Idiopathic Parkinson disease (PD) is the most common …

▪ Abstract Parkinson's disease (PD) is an age-related neurodegenerative disorder that
affects approximately 1 million persons in the United States. It is characterized by resting …

Abstract Purpose of Review The different parkinsonian conditions can be challenging to
separate clinically. This review highlights the important clinical features that guide the …

Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder mainly
characterized by degeneration of dopaminergic neurons in the substantia nigra and the …

Affective disorders, cognitive decline, and psychosis have long been recognized as common
in Parkinson disease (PD), and other psychiatric disorders include impulse control …

Background Our understanding of the natural history of idiopathic Parkinson's disease (PD)
remains limited. In the era of potential disease modifying therapies, there is an urgent need …

The definition of Parkinson's disease (PD) is changing with the expansion of clinical
phenomenology and improved understanding of environmental and genetic influences that …

Over a period of more than 50 years, the symptomatic treatment of the motor symptoms of
Parkinson disease (PD) has been optimized using pharmacotherapy, deep brain …

Since the first formal description of Parkinson disease (PD) two centuries ago, our
understanding of this common neurodegenerative disorder has expanded at all levels of …

In this review, the clinical features of Parkinson's disease, both motor and non‐motor, are
described in the context of the progression of the disease. Also briefly discussed are the …