Micromotor-based dual aptassay for early cost-effective diagnosis of neonatal sepsis

JM Gordón Pidal, L Arruza, M Moreno-Guzmán… - Microchimica Acta, 2024 - Springer
Given the long-life expectancy of the newborn, research aimed at improving sepsis
diagnosis and management in this population has been recognized as cost-effective, which …

On the move-sensitive fluorescent aptassay on board catalytic micromotors for the determination of interleukin-6 in ultra-low serum volumes for neonatal sepsis …

J Gordón, L Arruza, MD Ibáñez, M Moreno-Guzmán… - ACS …, 2022 - ACS Publications
A graphene oxide/nickel/platinum nanoparticle micromotor (MM)-based fluorescent
aptassay is proposed to determine interleukin-6 (IL-6) in serum samples from low-birth …

[HTML][HTML] OFF-ON on-the-fly aptassay for rapid and accurate determination of procalcitonin in very low birth weight infants with sepsis suspicion

JMG Pidal, L Arruza, M Moreno-Guzmán… - Sensors and Actuators B …, 2023 - Elsevier
A fast and reliable OFF-ON micromotors (MM)-based aptassay for rapid, sensitive, and
accurate determination of procalcitonin (PCT) as one of the leading neonatal sepsis …

Neonatal sepsis at point of care

A Jyoti, S Kumar, VK Srivastava, S Kaushik… - Clinica Chimica Acta, 2021 - Elsevier
Sepsis, which includes infection followed by inflammation, is one of the leading causes of
death among neonates worldwide. The major attribute of this disease process is …

Toward early diagnosis of late-onset sepsis in preterm neonates: dual magnetoimmunosensor for simultaneous procalcitonin and C-reactive protein determination in …

A Molinero-Fernandez, M Moreno-Guzman… - ACS …, 2019 - ACS Publications
Early diagnosis of sepsis, combining blood cultures and inflammation biomarkers, continues
to be a challenge, especially in very low birth weight (VLBW) infants because of limited …

Polymer-Based Micromotor Fluorescence Immunoassay for On-the-Move Sensitive Procalcitonin Determination in Very Low Birth Weight Infants' Plasma

Á Molinero-Fernández, M Moreno-Guzmán… - ACS …, 2020 - ACS Publications
A new fluorescence micromotor-based immunoassay (FMIm) has been developed for
procalcitonin (PCT) determination as an early sepsis diagnostic analytical tool. The …

Miniaturized protein microarray with internal calibration as point-of-care device for diagnosis of neonatal sepsis

P Buchegger, U Sauer, H Toth-Székély, C Preininger - Sensors, 2012 - mdpi.com
Neonatal sepsis is still a leading cause of death among newborns. Therefore a protein-
microarray for point-of-care testing that simultaneously quantifies the sepsis associated …

[HTML][HTML] Analytical micro and nano technologies meet sepsis diagnosis

JMG Pidal, Á Molinero-Fernández… - TrAC Trends in …, 2024 - Elsevier
Sepsis is one of the deadliest health disorders in the current century due to specific
limitations in early and differential diagnosis. Therefore, early diagnosis and appropriate …

Precision medicine for neonatal sepsis

S Ng, T Strunk, P Jiang, T Muk, PT Sangild… - Frontiers in molecular …, 2018 - frontiersin.org
Neonatal sepsis remains a significant cause of morbidity and mortality especially in the
preterm infant population. The ability to promptly and accurately diagnose neonatal sepsis …

[HTML][HTML] Point-of-care diagnostics for sepsis using clinical biomarkers and microfluidic technology

Z Bradley, N Bhalla - Biosensors and Bioelectronics, 2023 - Elsevier
Sepsis is a life-threatening immune response which is caused by a wide variety of sources
and is a leading cause of mortality globally. Rapid diagnosis and appropriate antibiotic …