[HTML][HTML] Maternal metabolic syndrome in pregnancy and child development at age 5: exploring mediating mechanisms using cord blood markers

J Kwok, LG Speyer, G Soursou, AL Murray, KA Fanti… - BMC medicine, 2023 - Springer
Background There is limited evidence on how the classification of maternal metabolic
syndrome during pregnancy affects children's developmental outcomes and the possible …

[HTML][HTML] Early ascending growth is associated with maternal lipoprotein profile during mid and late pregnancy and in cord blood

E Blanco Sequeiros, AK Tuomaala… - International Journal of …, 2023 - nature.com
Introduction Intrauterine conditions and accelerating early growth are associated with
childhood obesity. It is unknown, whether fetal programming affects the early growth and …

The newborn metabolome: Associations with gestational diabetes, sex, gestation, birth mode, and birth weight

T Mansell, A Vlahos, F Collier, AL Ponsonby… - Pediatric …, 2022 - nature.com
Background Pathways towards many adult-onset conditions begin early in life, even in utero.
Maternal health in pregnancy influences this process, but little is known how it affects …

[HTML][HTML] Metabolic syndrome in pregnancy and risk for adverse pregnancy outcomes: A prospective cohort of nulliparous women

JA Grieger, T Bianco-Miotto, LE Grzeskowiak… - PLoS …, 2018 - journals.plos.org
Background Obesity increases the risk for developing gestational diabetes mellitus (GDM)
and preeclampsia (PE), which both associate with increased risk for type 2 diabetes mellitus …

[HTML][HTML] Cord blood metabolic markers are strong mediators of the effect of maternal adiposity on fetal growth in pregnancies across the glucose tolerance spectrum …

IL Lee, ELM Barr, D Longmore, F Barzi, ADH Brown… - Diabetologia, 2020 - Springer
Aims/hypothesis We aimed to assess associations between cord blood metabolic markers
and fetal overgrowth, and whether cord markers mediated the impact of maternal adiposity …

[HTML][HTML] A prospective study of associations between in utero exposure to gestational diabetes mellitus and metabolomic profiles during late childhood and …

W Perng, BM Ringham, HA Smith, G Michelotti… - Diabetologia, 2020 - Springer
Aims/hypothesis This study aimed to:(1) identify metabolite patterns during late childhood
that differ with respect to exposure to maternal gestational diabetes mellitus (GDM);(2) …

[HTML][HTML] Metabolic profile in early pregnancy is associated with offspring adiposity at 4 years of age: the Rhea pregnancy cohort Crete, Greece

V Daraki, V Georgiou, S Papavasiliou, G Chalkiadaki… - PloS one, 2015 - journals.plos.org
Context Maternal pre-pregnancy obesity may increase the risk of childhood obesity but it is
unknown whether other metabolic factors in early pregnancy such as lipid profile and …

Prior preterm or small-for-gestational-age birth related to maternal metabolic syndrome

JM Catov, R Dodge, JM Yamal, JM Roberts… - Obstetrics & …, 2011 - journals.lww.com
OBJECTIVE: To estimate whether women who deliver small babies due to preterm birth or
growth restriction have excess risk for cardiovascular disease and diabetes later in life …

[HTML][HTML] Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries

R Kadakia, M Nodzenski, O Talbot, A Kuang, JR Bain… - Diabetologia, 2019 - Springer
Aims/hypothesis We aimed to determine the association of maternal metabolites with
newborn adiposity and hyperinsulinaemia in a multi-ethnic cohort of mother–newborn …

Cord metabolic profiles in obese pregnant women: insights into offspring growth and body composition

N Patel, C Hellmuth, O Uhl, K Godfrey… - The Journal of …, 2018 - academic.oup.com
Context Offspring exposed in utero to maternal obesity have an increased risk of later
obesity; however, the underlying mechanisms remain unknown. Objective To assess the …