Origin and dispersal history of Hepatitis B virus in Eastern Eurasia

B Sun, A Andrades Valtueña, A Kocher, S Gao… - Nature …, 2024 - nature.com
Hepatitis B virus is a globally distributed pathogen and the history of HBV infection in
humans predates 10000 years. However, long-term evolutionary history of HBV in Eastern …

Ten millennia of hepatitis B virus evolution

A Kocher, L Papac, R Barquera, FM Key, MA Spyrou… - Science, 2021 - science.org
Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health
problem, but its past diversity and dispersal routes are largely unknown. We generated HBV …

Contemporary and historical human migration patterns shape hepatitis B virus diversity

BI Potter, M Thijssen, NS Trovão, A Pineda-Peña… - Virus …, 2024 - academic.oup.com
Infection by hepatitis B virus (HBV) is responsible for approximately 296 million chronic
cases of hepatitis B, and roughly 880,000 deaths annually. The global burden of HBV is …

Ancient hepatitis B viruses from the Bronze Age to the Medieval period

B Mühlemann, TC Jones, PB Damgaard, ME Allentoft… - Nature, 2018 - nature.com
Hepatitis B virus (HBV) is a major cause of human hepatitis. There is considerable
uncertainty about the timescale of its evolution and its association with humans. Here we …

Unravelling the history of hepatitis B virus genotypes A and D infection using a full-genome phylogenetic and phylogeographic approach

EG Kostaki, T Karamitros, G Stefanou, I Mamais… - Elife, 2018 - elifesciences.org
Hepatitis B virus (HBV) infection constitutes a global public health problem. In order to
establish how HBV was disseminated across different geographic regions, we estimated the …

Dating the origin of hepatitis B virus reveals higher substitution rate and adaptation on the branch leading to F/H genotypes

D Paraskevis, K Angelis, G Magiorkinis… - Molecular Phylogenetics …, 2015 - Elsevier
The evolution of hepatitis B virus (HBV), particularly its origins and evolutionary timescale,
has been the subject of debate. Three major scenarios have been proposed, variously …

Origin and dissemination of hepatitis B virus genotype C in East Asia revealed by phylodynamic analysis and historical correlates

SYC Lin, BR Magalis, M Salemi… - Journal of viral hepatitis, 2019 - Wiley Online Library
Hepatitis B virus disease progression in East Asia is most frequently associated with
genotype C (HBV/C). The increasing availability of HBV/C genetic sequences and detailed …

[HTML][HTML] Enigmatic origin of hepatitis B virus: an ancient travelling companion or a recent encounter?

G Zehender, E Ebranati, E Gabanelli… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) is the leading cause of liver disease and infects an estimated 240
million people worldwide. It is characterised by a high degree of genetic heterogeneity …

Reconstruction of the origin and dispersal of the worldwide dominant Hepatitis B Virus subgenotype D1

NS Trovão, M Thijssen, B Vrancken… - Virus …, 2022 - academic.oup.com
Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus
(HBV). HBV-D1 is the dominant subgenotype in the Mediterranean basin, Eastern Europe …

Phylogeography of hepatitis B virus: The role of Portugal in the early dissemination of HBV worldwide

R Marcelino, IJ Ezeonwumelu, A Janeiro, P Mimoso… - Plos one, 2022 - journals.plos.org
In Portugal, the genetic diversity, origin of HBV and the Portuguese role in the dissemination
of HBV worldwide were never investigated. In this work, we studied the epidemic history and …