Background Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …

Use of whole-genome sequencing (WGS) for routine mycobacterial species identification
and drug susceptibility testing (DST) is becoming a reality. We compared the performances …

Background Nearly two decades after completion of the genome sequence of
Mycobacterium tuberculosis (MTB), and with the advent of next generation sequencing …

Whole-genome sequencing (WGS) is a newer alternative for tuberculosis (TB) diagnostics
and is capable of providing rapid drug resistance profiles while performing species …

Routine full characterization of Mycobacterium tuberculosis is culture based, taking many
weeks. Whole-genome sequencing (WGS) can generate antibiotic susceptibility profiles to …

The current methods available to diagnose antimicrobial-resistant Mycobacterium
tuberculosis infections require a positive culture or only test a limited number of resistance …

Analyzing whole-genome sequencing data of Mycobacterium tuberculosis complex (MTBC)
isolates in a standardized workflow enables both comprehensive antibiotic resistance …

Drug-resistant tuberculosis poses a persistent public health threat. The ReSeqTB platform is
a collaborative, curated knowledgebase, designed to standardize and aggregate global …

Background Whole genome sequencing (WGS) holds great potential for the management
and control of tuberculosis. Accurate analysis of samples with low mycobacterial burden …

Whole-genome sequencing (WGS) is now common as a result of new technologies that can
rapidly sequence a complete bacterial genome for US $500 or less. Many studies have …