Dendritic cells have the ability to efficiently present internalized antigens on major
histocompatibility complex (MHC) I molecules. This process is termed cross-presentation …

Antigen cross-presentation is critical in infectious and tumor immunity where cytotoxic T
lymphocytes are induced by dendritic cells specifically equipped with cellular machineries to …

Major histocompatibility complex class I (MHC I) presentation of exogenous antigens (cross‐
presentation) by dendritic cells (DC) is essential for CD8 T‐cell immunity. Most cells use …

Highlights•Dendritic cells internalize exogenous antigens for cross-presentation on MHC
I.•MHC I cross-presentation allows immune surveillance of viral infection and …

Presentation of exogenous antigens on MHC class I molecules, termed cross-presentation,
is essential for the induction of CD8 T-cell responses and is carried out by specialized …

Cross-priming refers to the induction of primary cytotoxic CD8+ T cell responses to antigens
that are not expressed in antigen presenting cells (APCs) responsible for T cell priming …

Cross-presentation, in which exogenous antigens are presented via MHC I complexes, is
involved both in the generation of anti-infectious and anti-tumoral cytotoxic CD8+ T cells and …

The induction of most CD8+ T cell responses by dendritic cells (DCs) requires the
presentation of peptides from internalized antigen by class I MHC molecules. Increasing …

Antigen cross-presentation, the process in which exogenous antigens are presented on
MHC class I molecules, is crucial for the generation of effector CD8+ T cell responses …

The presentation of exogenous antigens on MHC class I molecules, known as cross-
presentation, is essential for the initiation of CD8+ T cell responses. In vivo, cross …