Purpose Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease with synovitis
as pathological changes. The immune microenvironment of RA promotes metabolic …

Recent studies have shown the significance of metabolic reprogramming in immune and
stromal cell function. Yet, the metabolic reconfiguration of RA macrophages (MΦs) is …

Recent studies have revealed a relationship between cellular metabolism and cell function
in immune cells. Cellular metabolism not only provides supplemental ATP, but also supports …

An increasing number of findings highlight the fundamental role of metabolism in
autoimmunity. This growing recognition of metabolic irregularities being a factor of immune …

Systemic lupus erythematosus (SLE) is a typical autoimmune disease characterized by
chronic inflammation and pathogenic auto-antibodies. Apart from B cells, dysregulation of …

Immune cells constantly patrol the body via the bloodstream and migrate into multiple
tissues where they face variable and sometimes demanding environmental conditions …

Systemic lupus erythematosus (SLE) is a complex autoimmune disease, characterized by a
breakdown of immune tolerance and the development of autoantibodies against nucleic self …

Like other autoimmune diseases, rheumatoid arthritis (RA) develops in distinct stages, with
each phase of disease linked to immune cell dysfunction. HLA class II genes confer the …

Immune cells undergo different metabolic pathways or immunometabolisms to interact with
various antigens. Immunometabolism links immunological and metabolic processes and is …

All immune cells depend on specific and efficient metabolic pathways to mount an
appropriate response. Over the past decade, the field of immunometabolism has expanded …