[HTML][HTML] Salidroside prevents PM2. 5-induced BEAS-2B cell apoptosis via SIRT1-dependent regulation of ROS and mitochondrial function

H Shan, X Li, C Ouyang, H Ke, X Yu, J Tan… - Ecotoxicology and …, 2022 - Elsevier
PM2. 5 is a harmful air pollutant currently threatening public health. It has been closely
linked to increased morbidity of bronchial asthma and lung cancer worldwide. Salidroside …

Salidroside pretreatment alleviates PM2. 5 caused lung injury via inhibition of apoptosis and pyroptosis through regulating NLRP3 Inflammasome

S Shi, D Huang, Y Wu, C Pei, Y Wang, Z Shen… - Food and Chemical …, 2023 - Elsevier
Ambient fine particulate matter (PM 2.5) is considered a leading cause of pathogenic
particulate matter induced lung injury. And Salidroside (Sal), the major bioactive constituent …

Sodium tanshinone IIA sulfonate attenuates cigarette smoke extract-induced mitochondrial dysfunction, oxidative stress, and apoptosis in alveolar epithelial cells by …

R Guan, H Yao, Z Li, J Qian, L Yuan, Z Cai… - Toxicological …, 2021 - academic.oup.com
Emphysema is one of the most important phenotypes for chronic obstructive pulmonary
disease (COPD). Apoptosis in alveolar epithelial cells (AECs) causes the emphysematous …

Salidroside attenuates ventilation induced lung injury via SIRT1-dependent inhibition of NLRP3 inflammasome

Y Wang, CF Xu, YJ Liu, YF Mao, Z Lv, SY Li… - Cellular Physiology and …, 2017 - karger.com
Background: Salidroside (SDS) is the main effective ingredient of Rhodiola rosea L with a
variety of pharmacologic properties. We aim to investigate the effects of SDS on ventilation …

SIRT1 mediates salidroside‐elicited protective effects against MPP+‐induced apoptosis and oxidative stress in SH‐SY5Y cells: involvement in suppressing MAPK …

CY Wang, ZN Sun, MX Wang… - Cell biology …, 2018 - Wiley Online Library
Parkinson's disease (PD) is a progressive neurodegenerative disease, leading to tremor,
rigidity, bradykinesia, and gait impairment. Salidroside has been reported to exhibit …

Resveratrol attenuates methylglyoxal-induced mitochondrial dysfunction and apoptosis by Sestrin2 induction

K Seo, S Seo, JY Han, SH Ki, SM Shin - Toxicology and applied …, 2014 - Elsevier
Methylglyoxal is found in high levels in the blood and other tissues of diabetic patients and
exerts deleterious effects on cells and tissues. Previously, we reported that resveratrol, a …

Salidroside intensifies mitochondrial function of CoCl2-damaged HT22 cells by stimulating PI3K-AKT-MAPK signaling pathway

Y Hou, Y Zhang, S Jiang, N Xie, Y Zhang, X Meng… - Phytomedicine, 2023 - Elsevier
Abstract Background Salidroside (Sal), an active component from Rhodiola crenulata, has
been confirmed to exert neuroprotective effects against hypoxia. However, its molecular …

PM2. 5 induces male reproductive toxicity via mitochondrial dysfunction, DNA damage and RIPK1 mediated apoptotic signaling pathway

J Zhang, J Liu, L Ren, J Wei, J Duan, L Zhang… - Science of The Total …, 2018 - Elsevier
Recent years, air pollution has been a serious problem, and PM 2.5 is the main air
particulate pollutant. Studies have investigated that PM 2.5 is a risky factor to the …

Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction

X Zhu, F Wang, X Lei, W Dong - Experimental Biology and …, 2021 - journals.sagepub.com
Bronchopulmonary dysplasia is a severe and long-term pulmonary disease in premature
infants. Hyperoxia-induced acute lung injury plays a critical role in bronchopulmonary …

Resveratrol decreases cell apoptosis through inhibiting DNA damage in bronchial epithelial cells

YUN Zhang, L Guo, BYK Law… - International …, 2020 - spandidos-publications.com
One of the major risk factors for asthma development is exposure to environmental
allergens. House dust mites (HDM) can induce DNA damage, resulting in asthma …