The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium
Aqueous humor outflow resistance is the primary determinant of intraocular pressure (IOP),
and increased outflow resistance is the basis for elevated IOP associated with glaucoma …
and increased outflow resistance is the basis for elevated IOP associated with glaucoma …
Intraocular pressure and the mechanisms involved in resistance of the aqueous humor flow in the trabecular meshwork outflow pathways
Intraocular pressure (IOP), the critical risk factor for glaucoma, is generated and maintained
by the aqueous humor circulation system. Aqueous humor is secreted from the epithelial …
by the aqueous humor circulation system. Aqueous humor is secreted from the epithelial …
[HTML][HTML] Normal and glaucomatous outflow regulation
Glaucoma remains only partially understood, particularly at the level of intraocular pressure
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …
What controls aqueous humour outflow resistance?
M Johnson - Experimental eye research, 2006 - Elsevier
The bulk of aqueous humour outflow resistance is generated in or near the inner wall
endothelium of Schlemm's canal in normal eyes, and probably also in glaucomatous eyes …
endothelium of Schlemm's canal in normal eyes, and probably also in glaucomatous eyes …
[HTML][HTML] Aqueous outflow-A continuum from trabecular meshwork to episcleral veins
T Carreon, E van der Merwe, RL Fellman… - Progress in retinal and …, 2017 - Elsevier
In glaucoma, lowered intraocular pressure (IOP) confers neuroprotection. Elevated IOP
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …
characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased …
Current understanding of conventional outflow dysfunction in glaucoma
Current understanding of conventional outflow dysfunction in... : Current Opinion in
Ophthalmology Current understanding of conventional outflow dysfunction in glaucoma …
Ophthalmology Current understanding of conventional outflow dysfunction in glaucoma …
The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment
Intraocular pressure (IOP) is the critical risk factor for glaucoma, a neurodegenerative
disease and frequent cause of blindness worldwide. As of today, all effective strategies to …
disease and frequent cause of blindness worldwide. As of today, all effective strategies to …
[HTML][HTML] The juxtacanalicular region of ocular trabecular meshwork: a tissue with a unique extracellular matrix and specialized function
The trabecular meshwork (TM) is a filter-like tissue located in the anterior segment of the
eye. It is composed of a series of fenestrated beams through which aqueous humor flows to …
eye. It is composed of a series of fenestrated beams through which aqueous humor flows to …
Modulation of outflow resistance by the pores of the inner wall endothelium.
The juxtacanalicular connective tissue (JCT) is widely believed to generate the bulk of
aqueous humor outflow resistance, while the pores of the inner wall endothelium are …
aqueous humor outflow resistance, while the pores of the inner wall endothelium are …
The trabecular meshwork outflow pathways: structural and functional aspects
ER Tamm - Experimental eye research, 2009 - Elsevier
The major drainage structures for aqueous humor (AH) are the conventional or trabecular
outflow pathways, which are comprised of the trabecular meshwork (made up by the uveal …
outflow pathways, which are comprised of the trabecular meshwork (made up by the uveal …