The interplay between the vaginal microbiome and innate immunity in the focus of predictive, preventive, and personalized medical approach to combat HPV-induced …

E Kudela, A Liskova, M Samec, L Koklesova… - EPMA Journal, 2021 - Springer
HPVs representing the most common sexually transmitted disease are a group of
carcinogenic viruses with different oncogenic potential. The immune system and the vaginal …

Microbiome and cervical cancer

CP Castanheira, ML Sallas, RAL Nunes, NPC Lorenzi… - Pathobiology, 2021 - karger.com
Persistent infection with some types of mucosal human papillomavirus (HPV) is the
etiological factor for the development of cervical cancer and its precursor lesions. Besides …

[HTML][HTML] Research of the potential biomarkers in vaginal microbiome for persistent high-risk human papillomavirus infection

X Chao, T Sun, S Wang, X Tan, Q Fan… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Vaginal dysbiosis may paly role in increased risk of human papillomavirus
(HPV) infection. This study aims to explore potential vaginal microbiome biomarkers, to …

[HTML][HTML] The role of the cervicovaginal microbiome on the genesis and as a biomarker of premalignant cervical intraepithelial neoplasia and invasive cervical cancer

G Curty, PS de Carvalho, MA Soares - International journal of molecular …, 2019 - mdpi.com
The microbiome is able to modulate immune responses, alter the physiology of the human
organism, and increase the risk of viral infections and development of diseases such as …

[HTML][HTML] Role of immunity and vaginal microbiome in clearance and persistence of human papillomavirus infection

L Ntuli, A Mtshali, G Mzobe, LJP Liebenberg… - Frontiers in cellular …, 2022 - frontiersin.org
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

[HTML][HTML] The complex interplay between vaginal microbiota, HPV infection, and immunological microenvironment in cervical intraepithelial neoplasia: a literature …

B Gardella, MF Pasquali, M La Verde, S Cianci… - International Journal of …, 2022 - mdpi.com
Background: in recent years, many studies were carried out to explore the role of vaginal
microbiota in HPV infections and cervical intraepithelial neoplasia (CIN) progression. The …

Association of cervicovaginal dysbiosis mediated HPV infection with cervical intraepithelial neoplasia

S Kumari, VM Bhor - Microbial Pathogenesis, 2021 - Elsevier
Cellular transformation to malignancy is a multifactorial process strongly linked with
microbiome dysbiosis. The female reproductive tract (FRT) is inhabited by specific …

[HTML][HTML] Association between cervical microbiota and HPV: could this be the key to complete cervical cancer eradication?

E Cascardi, G Cazzato, A Daniele, E Silvestris… - Biology, 2022 - mdpi.com
Simple Summary The microbiota can modulate immune responses and modify the
physiology of the human organism, thereby increasing infective risks and a neoplastic …

[HTML][HTML] Association of high-risk human papillomavirus infection duration and cervical lesions with vaginal microbiota composition

J Liu, M Luo, Y Zhang, G Cao… - Annals of Translational …, 2020 - ncbi.nlm.nih.gov
Background Cervical cancer is reportedly caused by the synergistic effects of persistent high-
risk human papillomavirus (HPV) infection. Cervical microbiota represent a unique and …

Vaginal microbiota and HPV infection: novel mechanistic insights and therapeutic strategies

Y Li, T Yu, H Yan, D Li, T Yu, T Yuan… - Infection and drug …, 2020 - Taylor & Francis
Cervical cancer is a global public health concern. The complex interaction of genetic and
environmental factors is critical for the progress of cervical cancer. Growing evidence …