[PDF][PDF] The input-output relationship of the cholinergic basal forebrain

MR Gielow, L Zaborszky - Cell reports, 2017 - cell.com
Basal forebrain cholinergic neurons influence cortical state, plasticity, learning, and
attention. They collectively innervate the entire cerebral cortex, differentially controlling …

Diverse spatiotemporal scales of cholinergic signaling in the neocortex

AA Disney, MJ Higley - Journal of Neuroscience, 2020 - Soc Neuroscience
ACh is a signaling molecule in the mammalian CNS, with well-documented influence over
cognition and behavior. However, the nature of cholinergic signaling in the brain remains …

[PDF][PDF] Molecularly defined and functionally distinct cholinergic subnetworks

X Li, H Yu, B Zhang, L Li, W Chen, Q Yu, X Huang… - Neuron, 2022 - cell.com
Cholinergic neurons in the medial septum (MS) constitute a major source of cholinergic
input to the forebrain and modulate diverse functions, including sensory processing …

Fast modulation of visual perception by basal forebrain cholinergic neurons

L Pinto, MJ Goard, D Estandian, M Xu, AC Kwan… - Nature …, 2013 - nature.com
The basal forebrain provides the primary source of cholinergic input to the cortex, and it has
a crucial function in promoting wakefulness and arousal. However, whether rapid changes …

Specific basal forebrain–cortical cholinergic circuits coordinate cognitive operations

L Záborszky, P Gombkoto, P Varsanyi… - Journal of …, 2018 - Soc Neuroscience
Based on recent molecular genetics, as well as functional and quantitative anatomical
studies, the basal forebrain (BF) cholinergic projections, once viewed as a diffuse system …

[PDF][PDF] Central cholinergic neurons are rapidly recruited by reinforcement feedback

B Hangya, SP Ranade, M Lorenc, A Kepecs - Cell, 2015 - cell.com
Basal forebrain cholinergic neurons constitute a major neuromodulatory system implicated
in normal cognition and neurodegenerative dementias. Cholinergic projections densely …

[HTML][HTML] Cell-type-specific modulation of neocortical activity by basal forebrain input

HJ Alitto, Y Dan - Frontiers in systems neuroscience, 2013 - frontiersin.org
Activation of the cholinergic neurons in the basal forebrain (BF) desynchronizes cortical
activity and enhances sensory processing during arousal and attention. How the cholinergic …

Optogenetic dissection of the basal forebrain neuromodulatory control of cortical activation, plasticity, and cognition

SC Lin, RE Brown, MGH Shuler… - Journal of …, 2015 - Soc Neuroscience
The basal forebrain (BF) houses major ascending projections to the entire neocortex that
have long been implicated in arousal, learning, and attention. The disruption of the BF has …

A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes

B Robert, EY Kimchi, Y Watanabe, T Chakoma, M Jing… - Elife, 2021 - elifesciences.org
Basal forebrain cholinergic neurons (BFCNs) project throughout the cortex to regulate
arousal, stimulus salience, plasticity, and learning. Although often treated as a monolithic …

Impact of basal forebrain cholinergic inputs on basolateral amygdala neurons

CT Unal, D Pare, L Zaborszky - Journal of Neuroscience, 2015 - Soc Neuroscience
In addition to innervating the cerebral cortex, basal forebrain cholinergic (BFc) neurons send
a dense projection to the basolateral nucleus of the amygdala (BLA). In this study, we …