Acute bacterial inflammation is accompanied by excessive release of bacterial toxins and
production of reactive oxygen and nitrogen species (ROS and RNS), which ultimately results …

Oxidative stress generated during ischemia/reperfusion injury has been shown to augment
cellular responsiveness. Whereas oxidants are themselves known to induce several …

The transition of macrophages from the pro-inflammatory M1 to the anti-inflammatory M2
phenotype is crucial for the progression of normal wound healing. Persistent M1 …

Sepsis is described as a systemic immune response of the body to an infectious process that
might result in dysfunctional organs that may lead to death. In clinical practice, sepsis is …

Sepsis, a systemic inflammatory response to infection, is the leading cause of death in the
intensive care unit (ICU). Previous studies indicated that mesenchymal stromal cells (MSCs) …

Although bone marrow–derived mesenchymal stem cell (MSC) systemic administration
reduces sepsis-associated inflammation, organ injury, and mortality in clinically relevant …

Human Mesenchymal Stem/Stromal Cells (MSCs) have been reported to produce an M2-
like, alternatively activated phenotype in macrophages. In addition, MSCs mediate effective …

Sepsis is a syndrome of acute organ dysfunction caused by the physiologic and
pathophysiologic response to infection [1–3]. Although the specific clinical definition of …

Over the past 15 years, mesenchymal stem cells (MSCs) have been assessed for their
capacity to suppress inflammation and promote tissue repair. Regardless of whether the …

Sepsis is a life-threatening process due to organ dysfunction resulting from severe
infections. Mesenchymal stromal cells (MSCs) are being investigated as therapy for sepsis …