[HTML][HTML] Behavioral variant frontotemporal dementia associated with GRN and ErbB4 gene mutations: a case report and literature review

Y Cai, Z Peng, Q He, P Sun - BMC Medical Genomics, 2024 - Springer
Objective To report the clinical manifestation and genetic characteristics of a patient having
frontotemporal dementia (FTD) with abnormal behavior and unstable walking. Methods The …

ErbB4 mutation that decreased NRG1-ErbB4 signaling involved in the pathogenesis of amyotrophic lateral sclerosis/frontotemporal dementia

L Sun, B Cheng, Y Zhou, Y Fan, W Li… - Journal of …, 2020 - content.iospress.com
Background: Amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) includes a
large spectrum of neurodegenerative disorders. Objective: To identify the relationship of …

GRN mutation in a patient with a behavioral variant of frontotemporal lobar degeneration (bvFTD)

S Walczysková, P Ressner, Š Hilscherová… - Folia …, 2017 - termedia.pl
The clinical spectrum of frontotemporal lobar degeneration (FTLD) is characterized by
personality changes, language impairment, and executive function deficits. About 40% of …

Narcissistic Personality Disorder as Prodromal Feature of Early-Onset, GRN-Positive bvFTD: A Case Report

M Michelutti, D Urso, V Gnoni, A Giugno… - Journal of …, 2024 - content.iospress.com
Background: Behavioral variant frontotemporal dementia (bvFTD) typically involves subtle
changes in personality that can delay a timely diagnosis. Objective: Here, we report the case …

[HTML][HTML] The frequency of genetic mutations associated with behavioral variant frontotemporal dementia in Chinese Han patients

L Liu, B Cui, M Chu, Y Cui, D Jing, D Li… - Frontiers in aging …, 2021 - frontiersin.org
Background Behavioral variant frontotemporal dementia (bvFTD) is a clinically
heterogeneous syndrome with high heredity. However, the frequencies of mutations …

Clinical, neuropathological, and genetic characteristics of the novel IVS9+ 1delG GRN mutation in a patient with frontotemporal dementia

R Taipa, A Tuna, J Damásio, PS Pinto… - Journal of …, 2012 - content.iospress.com
Frontotemporal lobar degeneration (FTLD) refers to a clinically, pathologically, and
genetically heterogeneous group of dementias that arises from the degeneration of the …

Frequency of GRN‐associated cases in a Russian cohort of patients with frontotemporal dementia

Y Shpilyukova, E Fedotova… - Alzheimer's & …, 2021 - Wiley Online Library
Background Frontotemporal dementia (FTD) is the second most common cause of early‐
onset neurodegenerative dementia. Up to 40% of FTD cases are inherited. Mutations in …

GRN mutation spectrum and genotype–phenotype correlation in Chinese dementia patients: data from PUMCH dementia cohort

C Liu, L Dong, J Wang, J Li, X Huang, D Lei… - Journal of Medical …, 2024 - jmg.bmj.com
Background Methods The GRN mutations, especially of the loss of function type, are
causative of frontotemporal dementia (FTD). However, several GRN variants can be found in …

Novel GRN mutations in Alzheimer's disease and frontotemporal lobar degeneration

I Piaceri, D Imperiale, E Ghidoni… - Journal of …, 2018 - content.iospress.com
Background: During the twentieth century, frontotemporal dementia (FTD) was often
misdiagnosed, confused with Alzheimer's disease or psychiatric disorders, jeopardizing care …

[HTML][HTML] GRN frontotemporal dementia

GYR Hsiung, HH Feldman - 2020 - europepmc.org
The spectrum of GRN frontotemporal dementia (GRN-FTD) includes the behavioral variant
(bvFTD), primary progressive aphasia (PPA; further subcategorized as progressive …